Abstract:Endothelin-1 (ET-1) is a powerful physiological vasoconstrictor release in response to endothelial injury. Increased synthesis of endothelin is associated with myocardial ischemia and reperfusion injury. The normal level varies between 0.2 and 18.5 pg/mL that maintains normal vascular homeostasis. We hypothesized that there exists a correlation between ET-1 and clinical outcome in patient undergoing elective coronary artery bypass grafting (CABG) surgery under cardiopulmonary bypass.Fifty-eight patients underg… Show more
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