The epidemiology of lumbar degenerative spondylolisthesis (DS) has been controversial. We recently performed a systemic review with the aim to have a better understanding of DS's prevalence in general population. The results showed the prevalence of DS is very gender specific and age specific (1). Both women and men have few DS before 50 years old, after 50 years old both women and men start to develop DS, with women having a faster developing rate than men. For elderly Chinese (mean age, 72.5 years), DS prevalence is around 25.0% for women and 19.1% for men, and the prevalence women:men ratio is 1.3:1. Elderly Caucasian American may have a higher DS prevalence, being approximately 60-70% higher than elderly Chinese; however the prevalence women:men ratio was similar to elderly Chinese population (1). The majority of symptomatic DS patients are successfully treated without surgery. Physical therapy is the first line of treatment for adults with symptoms from spondylolisthesis. Hamstring stretching, trunk strengthening, and avoidance of inciting activities are beneficial for adults. Surgical management is offered when nonoperative options have not adequately relieved symptoms. Patients for whom surgery is indicated usually have good outcomes. Young patients may require only a fusion in situ; however, patients who have evidence of neural compression may need a decompression to relieve symptoms, and fusion is usually also indicated in these cases (2,3). In our last study (1), preliminary data showed the ratio of numbers of female patients received treatment compared with men did not differ between Northeast Asians (Chinese, Japanese, and Korean) and European and American Caucasians, being around 2:1 in elderly population. However, compared with Caucasians, Asians were likely to have surgical treatment more than half decade earlier (1). We were interested whether it was due to Northeast Asians manifest clinical symptoms earlier or more severe, and therefore did this further literature analysis. We used the PubMed search results we obtained for our last paper (1). To broadly include data, only the word 'spondylolisthesis' was used for search, and updated till September 18, 2016. We selected original research data involving surgical treatment of DS and published after year 2000, and reported from Japan [n=37 series, references (4-28)], South Korea [n=11, references (29-38)], mainland China [n=5 series, references (39-41)], and Taiwan [n=3 series, references (42,43)], America [(n=20 series, references (44-56)], and Europe [n=23 series, references (57-72)]. With the publications used for this analysis, European countries included Germany,