Does metabolic alkalosis influence cerebral oxygenation in infantile hypertrophic pyloric stenosis?

Nissen, Matthias; Cernaianu, Grigore; Thränhardt, René; Vahdad, Mohammad Reza; Barenberg, Karin; Tröbs, Ralf-Bodo

doi:10.1016/j.jss.2017.01.019

Cited by 6 publications

(14 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All studies demonstrate a negative correlation. Two studies show no association (9,11) and six studies do not report on possible associations (10,13,15,(17)(18)(19)).…”

Section: Blood Glucose Level and Cerebral Oxygenationmentioning

confidence: 91%

“…Twelve studies were identified, which describe blood glucose level measurements in combination with cerebral NIRS measurements ( Table 1) (6,(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Four studies describe an association (6,12,14,16) between blood glucose levels and cerebral oxygenation.…”

Section: Blood Glucose Level and Cerebral Oxygenationmentioning

confidence: 99%

“…Three studies demonstrate no association (11,23,29) and 14 do not report on possible associations (13, 15, 16, 18, 20-22, 24-28, 30, 31). Five studies include blood glucose level as well as blood lactate level (11,13,15,16,18).…”

Section: Blood Lactate Level and Cerebral Oxygenationmentioning

confidence: 99%

See 2 more Smart Citations

Blood Glucose and Lactate Levels and Cerebral Oxygenation in Preterm and Term Neonates—A Systematic Qualitative Review of the Literature

et al. 2020

View full text Add to dashboard Cite

Background: Cerebral oxygenation monitored non-invasively by near-infrared spectroscopy (NIRS) is of increasing interest in neonatal care. Cerebral oxygenation is determined by cerebral oxygen delivery and cerebral oxygen consumption. Oxygen delivery as well as oxygen consumption might be influenced by metabolic parameters like blood glucose and lactate. Objective: The aim of the present systematic qualitative review is therefore to identify and summarize all studies, which describe cerebral oxygenation measured with NIRS and blood glucose and/or blood lactate levels in neonates. Data sources: A systematic search of Ovid Embase and PubMed was performed. Search terms included near-infrared spectroscopy, fractional tissue oxygen extraction, cerebral tissue oxygen saturation, regional cerebral tissue oxygen saturation, oxygenation, term, and preterm neonates, cesarean delivery, transition, after-birth, newborn, vaginal delivery, cesarean delivery, baby, neonatal transition, metabolism, lactate, glucose, and blood glucose level. Study selection/data synthesis: Studies analyzing cerebral oxygenation and blood glucose and/or blood lactate levels in neonates were included. Animal studies, duplicates, or studies in non-English language were excluded. Results: Twenty-five studies were identified that describe blood glucose and/or blood lactate levels as primary or secondary outcome parameters with additional measured cerebral oxygenation by NIRS in neonates. Twelve studies were included with blood glucose measurements: four described an association between blood glucose levels and cerebral oxygenation, two show no association, and six do not report on possible associations. Eighteen studies were included with lactate measurements: one describe an association between lactate levels and cerebral oxygenation, while three show no association and 14 do not report on possible associations.

show abstract

“…All studies demonstrate a negative correlation. Two studies show no association (9,11) and six studies do not report on possible associations (10,13,15,(17)(18)(19)).…”

Section: Blood Glucose Level and Cerebral Oxygenationmentioning

confidence: 91%

Section: Blood Glucose Level and Cerebral Oxygenationmentioning

confidence: 99%

See 1 more Smart Citation

Blood Glucose and Lactate Levels and Cerebral Oxygenation in Preterm and Term Neonates—A Systematic Qualitative Review of the Literature

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Nineteen studies used NIRS. [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] Fourteen of these measured only cerebral oxygenation and five combined cerebral oxygenation with cerebral blood flow (CBF) or cerebral autoregulation (Table 1). Five studies used aEEG -in four to measure cerebral activity [33][34][35][36] and in one, a large cohort study, to detect epileptic activity only (Table 2).…”

Section: Structured Literature Searchmentioning

confidence: 99%

“…Neuromonitoring of the surgical newborn 705 cerebral oxygenation, two studies found no significant changes in BP, 18,32 and the other two studies did not report BP values (Table 4). 19,31 Four studies aimed to find associations between cerebral oxygen desaturation and other peri-operative monitoring techniques. 22,25,26,28 One of these investigated the applicability of NIRS in neonates undergoing noncardiac surgery by comparing the event rate of hypoxia (defined as SpO 2 < 90%) measured with the conventional peripheral pulse oximeter with the event rate of hypoxia measured with NIRS (defined as >20% decline from cerebral oxygen saturation (rSO 2 ) baseline or an absolute decline in rSO 2 less than 40%, lasting for a minimum of 3 min) and found that NIRS events occurred two to three times more often than hypoxia measured with the conventional peripheral pulse oximeter.…”

Section: Structured Literature Searchmentioning

confidence: 99%

Towards integrative neuromonitoring of the surgical newborn

Costerus

Hoorn

Hendrikx

et al. 2020

European Journal of Anaesthesiology

View full text Add to dashboard Cite

BACKGROUND The altered neurodevelopment of children operated on during the neonatal period might be due to perioperative changes in the homeostasis of brain perfusion. Monitoring of vital signs is a standard of care, but it does not usually include monitoring of the brain. OBJECTIVES To evaluate methods of monitoring the brain that might be of value. We also wanted to clarify if there are specific risk factors that result in peri-operative changes and how this might be evaluated. DESIGN Systematic review. DATA SOURCES A structured literature search was performed in MEDLINE in Ovid, Embase, Cochrane CENTRAL, Web of Science and Google Scholar. ELIGIBILITY CRITERIA Studies in neonates who received peri-operative neuromonitoring were eligible for inclusion; studies on neurosurgical procedures or cardiac surgery with cardiopulmonary bypass and/or deep hypothermia cardiac arrest were excluded. RESULTS Nineteen of the 24 included studies, totalling 374 infants, reported the use of near-infrared spectroscopy. Baseline values of cerebral oxygenation greatly varied (mean 53 to 91%) and consequently, no coherent results were found. Two studies found a correlation between cerebral oxygenation and mean arterial blood pressure. Five studies, with in total 388 infants, used (amplitude-integrated) electroencephalography to study peri-operative brain activity. Overall, the brain activity decreased during anaesthesia and epileptic activity was more frequent in the peri-operative phase. The association between intra-operative cerebral saturation or activity and neuro-imaging abnormalities and/ or neurodevelopmental outcome was investigated in six studies, but no association was found. CONCLUSION Neuromonitoring with the techniques currently used will neither help our understanding of the altered neonatal pathophysiology, nor enable early detection of deviation from the norm. The modalities lack specificity and are not related to clinical (long-term) outcome or prognosis. Accordingly, we were unable to draw up a monitoring guideline.

show abstract

Anesthesia for Hypertrophic Pyloric Stenosis

2018

Anesthesiology

View full text Add to dashboard Cite

Does metabolic alkalosis influence cerebral oxygenation in infantile hypertrophic pyloric stenosis?

Cited by 6 publications

References 47 publications

Blood Glucose and Lactate Levels and Cerebral Oxygenation in Preterm and Term Neonates—A Systematic Qualitative Review of the Literature

Blood Glucose and Lactate Levels and Cerebral Oxygenation in Preterm and Term Neonates—A Systematic Qualitative Review of the Literature

Towards integrative neuromonitoring of the surgical newborn

Anesthesia for Hypertrophic Pyloric Stenosis

Contact Info

Product

Resources

About