2010
DOI: 10.1007/s10029-010-0705-9
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Does mesh offer an advantage over tissue in the open repair of umbilical hernias? A systematic review and meta-analysis

Abstract: The use of mesh in umbilical hernia repair results in decreased recurrence and similar wound complications rates compared to tissue repair for primary umbilical hernias.

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Cited by 106 publications
(65 citation statements)
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“…This is regarded as an acceptable recurrence rate. In one study, it was found that the recurrence rate was decreased tenfold since the use of mesh [11].…”
Section: Discussionmentioning
confidence: 99%
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“…This is regarded as an acceptable recurrence rate. In one study, it was found that the recurrence rate was decreased tenfold since the use of mesh [11].…”
Section: Discussionmentioning
confidence: 99%
“…A clear benefit of the laparoscopic approach is that it allows the operating surgeon to perform a diagnostic laparoscopy to detect possible other defects. In addition, laparoscopy makes it easier to place a sizeable mesh in an intraperitoneal position with an adequate overlap of the borders of defect [11]. The result for complications in the pooled laparoscopic mesh placement group could be biased.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…http://www.prisma-statement.org [15], f MOOSE statement: Metaanalysis of Observational Studies in Epidemiology [16] regardless wether the patient actually received the treatment or not [18]. 10 In some specific clinical situations, an equivalence or non-inferiority design is preferred. An equivalence study investigates whether a new treatment is equivalent to the control with respect to a predefined indifference.…”
Section: The Research Question and The Primary Endpointmentioning
confidence: 99%
“…For some less common conditions, a multi-centre approach is prerequisite to enrol a large enough cohort of patients. It is 10 According to the International Conference on Harmonisation (ICH) guidelines of Good Clinical Practice (GCP) a statistical test decision of a study should be conservative [18]. This is the rationale to use the ITT population for superiority studies and the PP population for equivalence studies.…”
Section: Mono-centre Versus Multi-centre Studiesmentioning
confidence: 99%