Does melanotan injections (TAN JAB) cause melanoma? A systemic review of the effects of melanotan injections

SMART: An Internet study of users experiences of synthetic tanning

“…There is a lack of research addressing the long term effects of Melanotan I and II despite clinicians reporting concerns around its use relating to increased skin pigmentation, rhabdomyolysis, systemic toxicity with sympathomimetic symptoms, renal dysfunction and reversible encephalopathy syndrome (Javed, Yarrow, & Hemmington Gorse, 2013;Kaski, Stafford, Mehta, Jenkins, & Malhotra, 2013;Nelson et al, 2012). Dysplastic changes in existing nevi, eruptive atypical melanocytic nevi or appearance of new lesions and freckles following melanotan use are common (Burian, 2013;Cardones, Rand, & Richnik, 2009;Cousen et al, 2009;Ferrandiz-Pulido, Fernandez-Figueras, Quer, & Ferrandiz, 2011;Hueso-Gabriel et al, 2012;Javed et al, 2013;Langan, Ramlogan, Jamieson, & Rhodes, 2009;Langan et al, 2010;Ong & Bowling, 2012;Paurobally et al, 2011;Reid, Fitzgerald, Fabre, & Kirby, 2013;Sivyer, 2012;Thestrup-Pedersen & Sondergaard, 2010).…”

“…Dysplastic changes in existing nevi, eruptive atypical melanocytic nevi or appearance of new lesions and freckles following melanotan use are common (Burian, 2013;Cardones, Rand, & Richnik, 2009;Cousen et al, 2009;Ferrandiz-Pulido, Fernandez-Figueras, Quer, & Ferrandiz, 2011;Hueso-Gabriel et al, 2012;Javed et al, 2013;Langan, Ramlogan, Jamieson, & Rhodes, 2009;Langan et al, 2010;Ong & Bowling, 2012;Paurobally et al, 2011;Reid, Fitzgerald, Fabre, & Kirby, 2013;Sivyer, 2012;Thestrup-Pedersen & Sondergaard, 2010). Cases of malignant melanomas have also been reported (Ellis, Kirkham, & Seukeran, 2009;Paurobally et al, 2011Paurobally et al, , 2013.…”