Does left ventricular function continue to influence mortality following contemporary percutaneous coronary intervention?

Abstract

LV impairment remains a strong predictor of early and late mortality after PCI. LV function assessment is integral in risk stratification and patient optimization and should be recommended, wherever feasible, before PCI.

Dynamic changes in left ventricular function after a percutaneous coronary intervention

“…Female sex, moderately impaired versus poor LVEF, and delayed performance of repeat echocardiography (≥3 months) emerged as independent predictors of LVEF recovery from impaired to preserved following PCI. Impaired baseline LVEF is a well-established predictor of mortality and major adverse cardiovascular events outcomes following elective PCI [1][2][3][4][5]. Our results are in agreement with a recent large analysis [2] of the British Cardiovascular Intervention Society data set that found a strong relationship between LVEF and mortality outcomes following PCI.…”

“…There is a well-established association between reduced baseline left ventricular ejection fraction (LVEF) and poor outcomes after a percutaneous coronary intervention (PCI) [1][2][3][4][5]. However, little is known about LVEF changes after elective PCI and the subsequent prognostic effect of LVEF improvement or decline.…”

Clinical effect of postconditioning in ST-elevation myocardial infarction patients treated with primary percutaneous coronary intervention: a meta-analysis of randomized controlled trials

“…The long-term clinical goal is the prevention of heart failure and improvement of LV contractile function, one of the predictors of long-term prognosis after PCI for AMI (de Silva et al, 2012). A metaanalysis with a small size (n=272) showed that postconditioning significantly reduced heart failure (Wei et al, 2012).…”

Ischaemic cardiomyopathy: pathophysiology, assessment and the role of revascularisation

“…LV dysfunction is a major determinant of outcome following CABG49–51 and percutaneous coronary intervention (PCI),52 53 however patients with ICM have the potential to gain a lot from revascularisation. The majority of the evidence of revascularisation in ICM comes from a large series of observational studies 35 36 54–66.…”