Does Kidney Transplantation Help Young Patients on Dialysis With Erectile Dysfunction? A Single-center Study

Hennawy, Hany M El; Safar, Omar; Faifi, Abdullah S Al; Shalkamy, Osama; Alqahatani, Yahia; Nazer, Weam El; Mahedy, Ahmed; Ali, Mohammed Abdelrahim; Atta, Eisa Al; Abdelaziz, Abdelaziz A.; Malki, Ahmed Al; Mirza, Naveed; Fageeh, Ali Al; Zaitoun, Mohammad F; Elatreisy, Adel

doi:10.1016/j.urology.2022.07.042

Cited by 4 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A non-concurrent cohort study included all patients who underwent different bulbar urethroplasty techniques at a tertiary care institute in Egypt from February 2013 to January 2021, after the study protocol approval from the institutional review board. We excluded sexually inactive patients with preoperative moderate or severe ED (IIEF5-15 score < 19) [ 14 ], older than sixty-five, and younger than eighteen. The study population was subdivided into two groups.…”

Section: Methodsmentioning

confidence: 99%

Erectile function after different techniques of bulbar urethroplasty: does urethral transection make a difference?

Shalkamy,

Elsalhy,

Alghamdi

et al. 2023

BMC Urol

Self Cite

View full text Add to dashboard Cite

Purpose We aimed to compare the impact of urethral transection after different techniques of bulbar urethroplasty on erectile function outcome. Materials and methods We retrospectively reviewed the records for 245 patients who underwent different urethroplasty techniques for bulbar urethral stricture between February 2013 and January 2021. The comparison between the transecting and non-transecting cohorts included patients’ demographics, clinicopathological features of the urethral stricture, post-urethroplasty erectile function, and success of urethroplasty. Outcomes were erectile function status verified by IIEF5-15 score at preoperative, three months, and 12 months post-surgery. We defined Post-urethroplasty ED as a decrease of 5 points or more. Results The urethroplasty success rate of the entire cohort was 86.9% after a mean follow-up of 45.59 ± 21 months. Out of 245 patients, 18 (7.3%) experienced 90-day complications. Transecting bulbar urethroplasty techniques were performed in 74 patients (30.2%), while non-transecting techniques were performed in 171 patients (69.8%). there were no differences between the cohorts regarding urethroplasty success (87.8% Vs. 86.5%, Mantel-Cox test p = 0.93) or postoperative complications (8.1% Vs. 7%, p = 0.73). Transient ED was evident in the transecting cohort as reported in 8.1% compared to 2.9% for the non-transecting (p = 0.07).Still, but de novo permanent ED was comparable (4.1% Vs. 2.9%, p = 0.65), for transecting and non-transecting, respectively. Conclusions Unfortunately, some patients who undergo transecting techniques of bulbar urethroplasty experience transient erectile dysfunction that can improve within the first post- urethroplasty year; however, de novo permanent erectile dysfunction is uncommon after different techniques of bulbar urethroplasty and is not predisposed by urethral transection.

show abstract

Section: Methodsmentioning

confidence: 99%

Erectile function after different techniques of bulbar urethroplasty: does urethral transection make a difference?

Shalkamy,

Elsalhy,

Alghamdi

et al. 2023

BMC Urol

Self Cite

View full text Add to dashboard Cite

show abstract

Renal Transplantation Enhances the Sildenafil Citrate Effectiveness in Patients with Erectile Dysfunction. A Single-Center Perspective

El Hennawy,

Safar,

Al Faifi

et al. 2024

Transplantation Proceedings

View full text Add to dashboard Cite

Time-dependent analysis of erectile dysfunction in kidney transplant recipients: insights from four distinct time periods

Pan,

Zheng,

Wang

et al. 2024

BMC Infect Dis

View full text Add to dashboard Cite

Background and intention Erectile dysfunction (ED) is an underappreciated clinical condition in men. This study aims to compare the dynamic changes in the distribution of ED among male kidney transplant recipients (mKTRs) in four epochs: end-stage renal disease period (ESRDp), early post-transplant period (EPTP), pre-COVID-19, and post-COVID-19. Methods General information was gathered through interviews, follow-ups, and medical records. The International Index of Erectile Function Questionnaire-5 was used to assess erectile function. The Mann–Whitney U test and chi-square test were used to analyze differences in ED strength. Univariate and logistic regression analyses were conducted to identify risk factors for ED. Results The database contains 230 mKTRs. In the ESRDp, 17.0% had normal erectile function, 53.5% had mild ED, 18.3% had moderate ED, and 11.3% had severe ED. In the EPTP, the distribution was 38.2% normal, 42.6% mild, 10.8% moderate, and 8.2% severe. In the pre-COVID-19 period, it was 34.3%, 47.3%, 10.4%, and 7.8%, and in the post-COVID-19 period, it was 23.0%, 45.6%, 21.3%, and 10.0%. Overall, erectile function improved after kidney transplant (KT). However, post-COVID-19, the proportion of erectile function significantly decreased compared to EPTP and pre-COVID-19 periods. Risk factors for post-pandemic ED included degree, Generalized Anxiexy Disorder-7, kidney donor type, postoperative time, hypertension and hemoglobin concentration. Conclusion KT improves erectile function in mKTRs within 5 years, but post-SARS-CoV-2 viral infection, ED worsens due to altered risk factors. These findings inform future research for comprehensive ED prevention and management strategies in this population.

show abstract

Does Kidney Transplantation Help Young Patients on Dialysis With Erectile Dysfunction? A Single-center Study

Cited by 4 publications

References 19 publications

Erectile function after different techniques of bulbar urethroplasty: does urethral transection make a difference?

Erectile function after different techniques of bulbar urethroplasty: does urethral transection make a difference?

Renal Transplantation Enhances the Sildenafil Citrate Effectiveness in Patients with Erectile Dysfunction. A Single-Center Perspective

Time-dependent analysis of erectile dysfunction in kidney transplant recipients: insights from four distinct time periods

Contact Info

Product

Resources

About