Does Instability during Standing Occur just after Transcutaneous Xenon Light Irradiation around the Stellate Ganglion?

Abstract

Abstract. [Purpose] This study investigated whether instability during standing occurs just after transcutaneous xenon light irradiation around the stellate ganglion.[Subjects] Thirty healthy volunteers were the subjects.[Methods] The subjects underwent two experimental sessions: 1) 10-minute xenon light irradiation around the bilateral stellate ganglions in a comfortable supine position (Xe-LISG); and 2) 10-minute rest in the same position as Xe-LISG (control). After Xe-LISG and the control, they stood up immediately and maintained quiet standing for 1 minute. The low frequency power (LF) and ratio of LF to the high frequency power (LF/HF) based on R-R intervals, and the total length (LNG) and rectangular area (REC) of the excursion of the center of foot pressure during quiet standing were examined. [Results] Although no significant changes of HF and LF/HF were observed before and after the control, HF after Xe-LISG was significantly greater than that before Xe-LISG, and LF/HF after Xe-LISG was significantly lower than that before Xe-LISG. Additionally, although no significant difference was observed between REC after Xe-LISG and that after the control, LNG after Xe-LISG was significantly longer than that after the control.[Conclusion] These results suggest that Xe-LISG causes not only parasympathetic predominance and sympathetic suppression but also instability during standing just after Xe-LISG.

Efficacy of Noninvasive Stellate Ganglion Blockade Performed Using Physical Agent Modalities in Patients with Sympathetic Hyperactivity-Associated Disorders: A Systematic Review and Meta-Analysis

“…Nacitarhan et al indicated that SGB performed using therapeutic US exerts positive effects on the autonomic nervous system by altering HRV parameters, particularly by reducing the low to high frequency power ratio [42]. Similar results were reported by Yoshida et al [34]. In this study, we identified significant sympatholytic effects immediately after noninvasive SGB, regardless of the electrophysical modality used.…”

“…Therefore, numerous noninvasive approaches for SGB employing physical agent modalities (PAMs) have been developed as alternatives to the conventional invasive anesthetic technique, including therapeutic ultrasound (US), transcutaneous electrical nerve stimulation (TENS), light irradiation using low-level laser therapy (LLLT), and xenon light and linearly polarized near-infrared (LPNIR) light irradiation near or over the stellate ganglion region. In addition, noninvasive SGB can be safely and conveniently performed in clinical practice, particularly in patients declining injections, having a high bleeding tendency, undergoing anticoagulant therapy, or having contraindications for nerve blockade, such as those with hemophilia [30–34]. In patients with neuropathic pain syndromes, the effects of SGB performed using light irradiation were similar to those of conventional intensive SGB, including improved blood flow through vasodilation and reduced pain by direct blockade of the afferent nociceptive signals traveling through sympathetic pathways [31, 33, 35–38].…”

“…In addition, noninvasive SGB can alleviate conditions associated with hypersympathetic tone [35, 45, 47, 64–68] and physiological changes associated with suppressed sympathetic activities in healthy adults [34, 37, 42, 56, 69–75]. Because of the heterogeneity of treatment protocols and study designs, careful interpretation of results and drawing of conclusions regarding the short- and long-term efficacy of noninvasive SGB are necessary.…”

Effects of xenon irradiation of the stellate ganglion region on fibromyalgia

“…Many studies have shown the effects of stellate ganglion irradiation (SGI) with various types of light in patients with diverse diseases who responded to SGB 14 , 16 ) . SGI, with its lack of serious side effects, may be a promising treatment method that could replace SGB 13 , 15 ) .…”