Does hyperthermic povidone-iodine lavage increase the apoptotic rate of residual cancer cell in patients with malignant pleural mesothelioma?—a prospective pilot study
Abstract:Background
Malignant pleural mesothelioma (MPM) is an incurable, late presenting primary cancer, conferring a survival of 8–14 months. Different intrapleural treatments have been tested as part of a multimodality approach to treat a select group of patients with limited disease, increasing survival. Recently, povidone-iodine has been shown to induce apoptosis in microscopic tumour cells
in vitro
, with no reported complications. This is the first
in vivo
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