Abstract:Tourniquet‐induced ischemia‐reperfusion (IR) leads to an increase in reactive oxygen species (ROS) production and tissue necrosis and apoptosis during reperfusion, which disrupts the recovery of skeletal muscle contraction. Hyperbaric oxygen (HBO) therapy exposes patients to high oxygen levels at an increased pressure, which increases the amount of ROS in tissues. Using HBO therapy as a pretreatment can promote ischemic tolerance by increasing antioxidant effects in these tissues before the IR injury. In this … Show more
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