Does home-based exercise improve body mass index in patients with type 2 diabetes?

Krousel‐Wood, Marie; Berger, Linley; Jiang, Xiaozhang; Blonde, Lawrence; Myers, Lucas A.; Webber, Lorraine

doi:10.1016/j.diabres.2007.08.028

Cited by 46 publications

(79 citation statements)

References 41 publications

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“…Hu et al (17) also reported an inverse association between physical activity and the risk of type 2 diabetes for nonobese subjects with normal glucose regulation, as well as subjects who were either obese or showed impaired glucose regulation (mean follow-up = 9.4 years). However, several studies reported that glycemic control did not improve with lifestyle modification and drug therapy (11,12). Krousel-Wood et al (11) reported that exercise interventions have the potential to reduce BMI in patients with diabetes but not reduce HbA 1c .…”

Section: Discussionmentioning

confidence: 99%

“…These lifestyle interventions, which generally included both physical activity and nutritional interventions, have been highly successful in preventing the onset of type 2 diabetes. Studies that failed to show improved glycemic control typically reported poor exercise compliance (11) or low-intensity exercise (12). However, most physical activity intervention studies focused on English speakers.…”

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confidence: 99%

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Supervised Exercise Program, BMI, and Risk of Type 2 Diabetes in Subjects With Normal or Impaired Fasting Glucose

et al. 2012

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OBJECTIVETo determine the association of regular exercise, BMI, and fasting glucose with the risk of type 2 diabetes and to predict the risk.RESEARCH DESIGN AND METHODSKorean subjects (n = 7,233; 40–79 years old) who were not diagnosed with diabetes at baseline were enrolled through the National Health Insurance Corporation. All participants underwent biennial examinations, and 1,947 of 7,233 subjects also underwent a 6-month program of moderate-intensity exercise (300 min/week) without dietary advice.RESULTSDuring follow-up (mean = 2 years), there were 303 incidents of type 2 diabetes in the nonexercise program group (n = 5,286) and 83 in the exercise program group (n = 1,947). After adjusting for confounders, the risk of type 2 diabetes was positively associated with BMI and inversely with regular exercise, especially among overweight/obese subjects. After further adjustment for BMI, the odds ratios for risk of diabetes associated without and with regular exercise were 1.00 and 0.77, respectively. Among subjects with normal fasting glucose, exercise reduced the diabetes risk; however, among those with impaired fasting glucose (IFG), the protective effect of exercise was found only among overweight/obese subjects. The overweight/obese subjects in the exercise program group exhibited improved fasting glucose compared with the nonexercise program group and showed 1.5 kg of weight loss and a 3-cm decrease in waist circumference. Among overweight/obese subjects with unchanged fasting glucose, weight loss was greater in the exercise program group.CONCLUSIONSRegular exercise reduces the risk of type 2 diabetes in overweight/obese individuals. Particularly, regular exercise and weight or waist circumference control are critical factors for preventing diabetes in overweight/obese individuals with IFG.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Supervised Exercise Program, BMI, and Risk of Type 2 Diabetes in Subjects With Normal or Impaired Fasting Glucose

et al. 2012

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“…Among patients with diabetes, the benefits of regular physical activity have been well documented [24]. It was shown that restrictions on dietary freedom have a major negative impact on QoL [25].…”

Section: Discussionmentioning

confidence: 99%

The well-being and treatment satisfaction of diabetic patients in primary care

Saatçı

Tahmiscioglu

Bozdemir

et al. 2010

Health and Quality of Life Outcomes

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BackgroundThe quality of life in patients with diabetes is reduced and emotional coping with the disease has great impact on patient well-being.ObjectivesThe aim of this study was to assess the psychological well-being and treatment satisfaction in patients with type 2 diabetes mellitus in primary care.Study Design and SettingPatients (n = 112) with type 2 diabetes mellitus diagnosis for at least six months were enrolled. The Well-Being Questionnaire-22 and the Diabetes Treatment Satisfaction Questionnaire were used. Physical examination and laboratory investigations were performed.ResultsThe rates of the achieved targets were 32.1% for hemoglobin A1c, 62.5% for cholesterol and 20.5% for blood pressure. The mean scores for the general well-being, depression, anxiety, positive well-being and energy were 44.40 ± 13.23 (range = 16-62), 12.65 ± 3.80 (range = 5-18), 10.57 ± 4.47 (range = 1-18), 12.00 ± 4.01 (range = 2-18), and 9.16 ± 2.47 (range = 2-12), respectively. The mean scores for the treatment satisfaction, perception for hyperglycemia and perception for hypoglycemia were 22.37 ± 9.53 (range = 0.00-36.00), 1.71 ± 1.59 (range = 0-6), and 0.51 ± 0.98 (range = 0-6), respectively. There were significant associations between the depression score and the educational status, compliance to diet and physical exercise, and diabetic complications; between the anxiety score and the educational status, glycemic control, compliance to diet and physical exercise; between the energy score and the educational status, compliance to physical exercise, and diabetic complications; between the positive well-being score and the educational status, compliance to diet and physical exercise, complications and type of treatment; between the general well-being score and the educational status, compliance for diet and physical exercise, and complications. Treatment satisfaction was significantly associated to the educational status, glycemic control and compliance to diet and physical exercise. A significant correlation was found between the treatment satisfaction and the well-being.ConclusionsIndividualized care of patients with diabetes should consider improving the quality of life. Psychosocial support should be provided to the patients with type 2 diabetes and the negative effects of psychopathological conditions on the metabolic control should be lessened.

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“…Generally, studies that failed to elicit this benefit have utilized interventions of low intensity 21,22 or low volume 41 or have reported poor adherence to the intervention. 42 Importantly, the definitive study on this to date, a randomized, controlled trial in 251 T2DM patients, reported improvements ranging from Ϫ0.38 to Ϫ0.97 percentage points in HbA 1c from exercise training that ranged from Ϸ135 to 270 minutes of exercise per week for 6 months. 40 Quantification of effects across trials reveals that the overall beneficial effect of exercise on HbA 1c levels is modest (average HbA 1c reduction Ϫ0.8%, 90% confidence interval [CI] Ϫ1.3% to Ϫ0.2%) 50 ; however, even these small improvements have been reported to be clinically significant in terms of the effects on an aggregate composite of macrovascular, microvascular, and nonvascular end points, similar to what is produced from an intensive pharmaceutical intervention.…”

Section: Glycemic Controlmentioning

confidence: 99%