Does hoarseness of voice from recurrent nerve paralysis after esophagectomy for carcinoma influence patient quality of life?

McKeown or Ivor Lewis totally minimally invasive esophagectomy for cancer of the esophagus and gastroesophageal junction: systematic review and meta-analysis

“…The difference in the incidence of RLN trauma is consistent with the literature regarding open procedures (23) and is explained by avoiding a cervical dissection close to the RLN. This is important, since it has been shown that RLN trauma is associated with increased incidence of pulmonary complications, postoperative ventilation time, intensive care length of stay and hospital length of stay (24)(25)(26). The lower blood loss volume that was found in patients undergoing minimally invasive Ivor Lewis esophagectomy can be explained by omitting a third stage, the incision and the associated blood loss.…”

Recurrent laryngeal nerve injury after esophagectomy for esophageal cancer: incidence, management, and impact on short- and long-term outcomes

“…The only study in which results regarding RLNP recovery after esophagectomy are published to date focused on quality of life 1 year after RLNP and found a significant deteriorated quality of life after permanent nerve paralysis due to esophagectomy (12). Hence, precautions to prevent RLNP can improve the outcomes after esophagectomy.…”

“…For 6/21 of these patients surgical intervention (medialization thyroplasty) was required. All treatment interventions for vocal cord paralysis were conducted after a median time of 16.5 [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] months after esophagectomy. Of all patients that underwent medialization thyreoplasty, 3/6 had no more RLNP symptoms afterwards 2/6 made a partial recovery from their RLNP, and 1/6 did not recover.…”

“…The incidence of RLNP after esophagectomy varies, ranging from 0% to 59% (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). These disparities have been attributed to variation in extent of lymph node dissection, surgical technique (two-or three stage), the size and T-stage of the primary tumor, and the means of RLN injury diagnosis (8,(19)(20)(21).…”

Beeinträchtigung der Lebensqualität bei Patienten mit einseitiger Rekurrensparese nach thoraxchirurgischen Eingriffen

“…Die einseitige Rekurrensparese ("unilateral recurrent laryngeal nerve paralysis", URLNP) nach thoraxchirurgischen Eingriffen ist mit Häufigkeiten zwischen 7,0 und 36,2% eine bekannte Komplikation [3,9,14,18,21,23], jedoch wird ihr in der klinischen Routine zu wenig Beachtung beigemessen. Unmittelbar nach thoraxchirurgischen Eingriffen stellt sich bei Patienten mit URLNP immer wieder die Frage nach der klinischen Notwendigkeit einer therapeutischen Intervention, da die Glottisschlussinsuffizienz aufgrund der resultierenden Dysphagie und Aspiration zu letalen Komplikationen, v.a.…”