Does Helicobacter pylori treatment improve the symptoms of globus hystericus?

Kasap, Elmas; Ayhan, Semin; Yüceyar, Hakan

doi:10.4318/tjg.2012.0507

Cited by 5 publications

(5 citation statements)

References 15 publications

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“…After discussion between reviewers, 26 papers were included for full-text review. 23-48 Twelve papers were subsequently excluded, yielding 14 that were identified for data collection and qualitative analysis. 23-34 Further details of the excluded papers may be found in Appendix A (available in the online version of the article).…”

Section: Resultsmentioning

confidence: 99%

“…A total of 1082 studies were identified through our literature search and reviewed ( Figure 1). After discussion between reviewers, 26 papers were included for full‐text review 23‐48 . Twelve papers were subsequently excluded, yielding 14 that were identified for data collection and qualitative analysis 23‐34 .…”

Section: Resultsmentioning

confidence: 99%

“…Twelve papers were subsequently excluded, yielding 14 that were identified for data collection and qualitative analysis. [23][24][25][26][27][28][29][30][31][32][33][34] Further details of the excluded papers may be found in Appendix A (available in the online version of the article). The details of the papers included in the analysis are located in Table 1.…”

Section: General Study Informationmentioning

confidence: 99%

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The Role of Helicobacter pylori in Laryngopharyngeal Reflux: A Systematic Review and Meta‐analysis

Campbell

Kilty

Hutton

et al. 2016

Otolaryngol.--head neck surg.

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Objective The primary objective was to determine the prevalence of Helicobacter pylori among patients with laryngopharyngeal reflux. The secondary objective was determining if H pylori eradication leads to greater symptom improvement in patients with laryngopharyngeal reflux as compared with standard proton pump inhibitor therapy alone. Data Sources EMBASE, Cumulative Index to Nursing and Allied Health Literature, MEDLINE, World Health Organization International Clinical Trials Registry Platform, European Union Clinical Trials Register, Cochrane Library databases of clinical trials, and ClinicalTrials.gov. Review Methods A systematic review was performed of studies assessing the diagnosis or treatment of H pylori among patients with laryngopharyngeal reflux. Randomized controlled trials, cohort studies, case-control studies, and case series were included. A meta-analysis of prevalence data and assessment of heterogeneity was performed on relevant studies. Results Fourteen studies were analyzed in the review, with 13 eligible for the meta-analysis. We determined that the prevalence of H pylori among patients with laryngopharyngeal reflux was 43.9% (95% confidence interval, 32.1-56.5). The heterogeneity of studies was high, with an overall I value of 92.3%. We were unable to quantitatively assess findings for our secondary outcome, since H pylori identification and treatment were not the primary focus of the majority of studies. Conclusion There is a high rate of H pylori infection among patients with laryngopharyngeal reflux. The infection rate in North America and Western Europe has not been adequately studied. There is insufficient evidence to make a recommendation regarding the testing and treatment of H pylori infection among patients with laryngopharyngeal reflux.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: General Study Informationmentioning

confidence: 99%

See 1 more Smart Citation

The Role of Helicobacter pylori in Laryngopharyngeal Reflux: A Systematic Review and Meta‐analysis

Campbell

Kilty

Hutton

et al. 2016

Otolaryngol.--head neck surg.

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“…However, there was no significant difference in the improvement in globus symptoms in patients who received only PPI treatment. 23 Additional studies are needed to understand the fundamental mechanisms leading to globus sensation in CHGM. These patients might benefit from H. pylori eradication therapy to alleviate this potentially aggravating factor.…”

Section: Discussionmentioning

confidence: 99%

Heterotopic Gastric Mucosa in the Proximal Esophagus (Inlet Patch): Endoscopic Prevalence, Clinico-pathological Characteristics and Its Association with Helicobacter pylori

Rathod

Anand

Ramesh

et al. 2022

Journal of Digestive Endoscopy

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Objective To determine the prevalence of the inlet patch (IP), its clinico-pathological features, and its association with Helicobacter pylori. Materials and Methods A prospective observational study was performed on 1,889 patients referred for esophagogastroduodenoscopy for various reasons, primarily for the evaluation of dyspepsia. All patients were enquired about the presence of symptoms and carefully examined for the presence of IP during upper gastrointestinal (GI) endoscopy. Biopsies were taken from the patients who had IP. Statistical Analysis All statistical analyses were performed using the Statistical Package for Social Sciences (SPSS) 13.0 software for Windows XP. Categorical variables were compared using the chi-squared test or Fisher's exact test and continuous variables were compared using Student's t-test and univariate analysis. A P-value of less than 0.05 was considered to be statistically significant. Results Inlet patches were found in 34 of 1,889 patients (1.8%). H. pylori was identified in 23.52% of patients (8/34) with IP. Gastric H. pylori infection was positive in all (08/08) patients who had IP. Colonization of H. pylori was more common in antral type mucosa (6/8). H. pylori positivity in the IP correlated with globus sensation symptom in our study, 87.5% of patients with IP and H. pylori positive had globus sensation. Conclusion The prevalence of IP seems to be underestimated. H. pylori colonization of the IP is common and it positively correlates with globus sensation and is closely related to the H. pylori density in the stomach. Though preneoplasia within IP is rare, which does not support the recommendation to regularly obtain biopsies for histopathology, it might be beneficial in a subset of patients with persistent globus sensation.

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“…E. Kasap и соавт. [16] выяви-ли наличие Helicobacter pylori у 75 (60%) из 123 пациентов с жалобами на КГ. Авторы отметили значительную редук-цию симптоматики КГ у пациентов, получавших эрадика-ционную терапию.…”

Section: этиологияunclassified

Paresthesias of the upper respiratory tract

Ai¹,

Ab²,

Sg³

et al. 2014

Vestn. otorinolaringol.

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ОБЗОРЫПарестезии верхних дыхательных путей -разновид-ность расстройства чувствительности в глотке, гортани. Клинические проявления парестезий верхних дыхатель-ных путей разнообразны, к ним относятся ощущение «кома в горле» (КГ), першения, покалывания, онемения в глотке, в проекции гортани. Парестезии часто сопровож-даются упорным кашлем, ощущением нехватки воздуха, затруднением глотания, дисфонией.Наиболее часто встречается жалоба на ощущение КГ, значительно ухудшающее качество жизни пациентов [1] -от 4,1 до 5% причин обращений к оториноларингологу [2].В анамнезе 46% практически здоровых людей отмече-ны эпизоды жалоб на ощущение КГ. Пациенты с этим симптомом обращаются за помощью к врачам разных специальностей: оториноларингологам, фониатрам, не-врологам, эндокринологам, гастроэнтерологам. Многие пациенты (78%) консультируются с онкологами, что объ-ясняется выраженной канцерофобией [3]. «Ком в горле» впервые был описан Гиппократом око-ло 2500 лет назад. До 70-х годов XIX века КГ обозначался 1 e-mail: info@mnpco.mosgorzdrav.ru 2 e-mail: guekht@mail.ru.

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Does Helicobacter pylori treatment improve the symptoms of globus hystericus?

Abstract: Girifl ve

Cited by 5 publications

References 15 publications

The Role of Helicobacter pylori in Laryngopharyngeal Reflux: A Systematic Review and Meta‐analysis

The Role of Helicobacter pylori in Laryngopharyngeal Reflux: A Systematic Review and Meta‐analysis

Heterotopic Gastric Mucosa in the Proximal Esophagus (Inlet Patch): Endoscopic Prevalence, Clinico-pathological Characteristics and Its Association with Helicobacter pylori

Paresthesias of the upper respiratory tract

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