Does gabapentin provide benefit for patients with knee OA? A benefit-harm and cost-effectiveness analysis

Etwa ein Drittel der Menschen mit einer symptomatischen Gonarthrose leidet nicht nur unter nozizeptiven Schmerzen, welche auf abnormen Belastungen im Gelenk beruhen, sondern zusätzlich unter noziplastischen Schmerzen, die nicht auf Gewebeschäden oder Schäden des somatosensorischen Systems zurückzuführen sind. Ist bei diesen Personen eine Behandlung mit Gabapentin unter klinischen und ökonomischen Gesichtspunkten gerechtfertigt?

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Assessment of Pain in Osteoarthritis of the Knee

Thirumaran

Deveza

Atukorala

et al. 2023

JPM

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Knee osteoarthritis (KOA) pain is a subjective and personal experience, making it challenging to characterise patients’ experiences and assess their pain. In addition, there is no global standard for the assessment of pain in KOA. Therefore, this article examines the possible methods of assessing and characterising pain in patients with KOA using clinical symptoms, pain assessment tools, and imaging. We examine the current methods of assessment of pain in KOA and their application in clinical practice and clinical trials. Furthermore, we explore the possibility of creating individualised pain management plans to focus on different pain characteristics. With better evaluation and standardisation of pain assessment in these patients, it is hoped that patients would benefit from improved quality of life. At the same time, improvement in pain assessment would enable better data collection regarding symptom response in clinical trials for the treatment of osteoarthritis.

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Does gabapentin provide benefit for patients with knee OA? A benefit-harm and cost-effectiveness analysis

Cited by 3 publications

References 41 publications

Temperature-Mediated Neural Interventions in Knee Osteoarthritis: a Review of Cryoneurolysis and Cooled Radiofrequency Ablation with Ultrasound Guidance

Temperature-Mediated Neural Interventions in Knee Osteoarthritis: a Review of Cryoneurolysis and Cooled Radiofrequency Ablation with Ultrasound Guidance

Gonarthrose: Nutzen-Risiko-Verhältnis und Kosteneffektivität von Gabapentin

Assessment of Pain in Osteoarthritis of the Knee

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