Does Chondrocalcinosis Affect Knee Society Scores and Range of Motion After TKA?

Lee, Gwo-Chin; Lotke, Paul A.

doi:10.1007/s11999-013-3447-z

Cited by 9 publications

(13 citation statements)

References 16 publications

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“…In one study [ 28 ], the presence of CC was additionally determined on postoperative radiographs. Whereas Lee et al [ 26 ] based their diagnostic criteria on the sole intraoperative, visual presence of CC and Willem et al [ 27 ] on the radiologically visible calcifications.…”

Section: Resultsmentioning

confidence: 99%

“…Besides one publication, all [21][22][23][25][26][27][28] reported a prevalence of CC at time of surgery between 12.6% and 36%. Lee et al [26] calculated a prevalence of 26.5% based on the intraoperative, visual presence of calcium deposition.…”

Section: Diagnostic Methods and Prevalencementioning

confidence: 99%

“…All included studies analysed the impact or the correlation of CC with the functional outcome, the survivorship and the progression of OA especially in UKA, but also in TKA without patellar resurfacing. There were five (62.5%) prospective cohort studies [21][22][23][24][25] and three retrospective cohort studies Knee Surgery, Sports Traumatology, Arthroscopy [26,27], of which one was with prospective data collection [28]. According to the "MINORS" appraisal tool for nonrandomized control trials, the mean global score was 19.5 for comparative studies.…”

Section: Study Characteristics and Quality Of Included Studiesmentioning

confidence: 99%

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Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review

Moret

Iordache

D’Ambrosi

et al. 2021

Knee Surg Sports Traumatol Arthrosc

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Purpose There are contentious data about the role calcium pyrophosphate (CPP) crystals and chondrocalcinosis (CC) play in the progression of osteoarthritis (OA), as well as in the outcomes after knee arthroplasty. Hence, the purpose of this systematic review was to analyse the clinical and functional outcome, progression of OA and prosthesis survivorship after unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) in patients with CC compared to patients without CC. Methods A systematic review of the literature in PubMed, Medline, Embase and Web of Science was performed using the “Preferred Reporting Items for Systematic Reviews and Meta-Analysis” (PRISMA) guidelines. Articles which reported the outcome and survival rates of prosthesis after TKA or UKA in patients with CC were included. Results A total of 3718 patient knees were included in eight selected publications, with a median sample sizes of 234 knees (range 78–1000) and 954 knees (range 408–1500) for publications including UKA and TKA, respectively. At time of surgery, the mean age was 69 years and the prevalence for CC ranged from 12.6 to 36%. Chondrocalcinosis did not significantly influence the functional and clinical outcome, the implant survival as well as the radiologic progression of OA disease after UKA and TKA. Conclusion The presence of CPP crystals in tissue samples, synovial fluid or evidence of calcifications on preoperative radiographs did not significantly influence the postoperative functional and activity scores. It also had no significant influence on prosthesis survival rate, whether it was a UKA or a TKA. This study shows that the impact of a subclinical form of chondrocalcinosis may not be of clinical relevance in the context of arthroplasty. Level of evidence IV.

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Section: Resultsmentioning

confidence: 99%

Section: Diagnostic Methods and Prevalencementioning

confidence: 99%

Section: Study Characteristics and Quality Of Included Studiesmentioning

confidence: 99%

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Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review

Moret

Iordache

D’Ambrosi

et al. 2021

Knee Surg Sports Traumatol Arthrosc

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“…11,12 Interestingly, one study estimated an incidence of 34% for chondrocalcinosis among 1500 primary total knee arthroplasties based on visual grading of visible crystal deposits observed intraoperatively. 13 Finally, another series examining CPPD in 608 cadaveric knee joints reported a prevalence of 13%. 14 In the literature, the presence (or absence) of CPPD documented in routine joint arthroplasties also appears quite variable.…”

Section: Discussionmentioning

confidence: 99%

The Incidence and Significance of Calcium Pyrophosphate Dihydrate Deposits in Histologic Examinations of Total Hip, Knee, and Shoulder Joint Arthroplasties

Dermawan

Goldblum

Reith

et al. 2021

Archives of Pathology &Amp; Laboratory Medicine

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Context.— The incidence, distribution, and significance of calcium pyrophosphate dihydrate deposition (CPPD) disease have not been extensively compared among various total joint resections. Objective.— To investigate and define the clinical and pathologic features of CPPD in hip, shoulder, and knee arthroplasties. Design.— We retrospectively reviewed consecutive total hip, knee, and shoulder arthroplasty cases (N = 3195) confirmed pathologically between January 1, 2017, and October 10, 2018, comparing clinical and pathologic data. Results.— Among 2004 hip arthroplasties, 61 (3%) had CPPD on pathologic examination; the majority had a histologic diagnosis of osteoarthritis followed by fracture and avascular necrosis. Of 1113 knee arthroplasties, 98 (9%) had CPPD; all had a histologic diagnosis of osteoarthritis. Among 78 shoulder arthroplasties, 10 (13%) had CPPD; all but one had a histologic diagnosis of osteoarthritis. Patients with hip and knee CPPD were significantly older than those without CPPD. Of the 169 pathologically detected CPPD cases, only 35 (21%) were documented on preoperative radiologic images or by other clinical means; radiology reports were significantly more likely to document chondrocalcinosis in the knees than in the hips. Histologically, CPPD were noted almost exclusively in the separately submitted soft tissues/joint capsule, concomitantly involving the articular cartilage surface in only 3.0% (5 of 169) of cases. Conclusions.— Calcium pyrophosphate dihydrate deposition is more than twice as likely to occur in the knees and shoulders compared with the hips. Patients with CPPD in the knees or hips are usually not recognized preoperatively/radiologically and constitute a significantly older population. Reliably establishing the diagnosis of CPPD requires pathologic examination of the submitted soft tissue/joint capsule.

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“…CC can be identified by plain radiographs or upon histological examination . Previous epidemiological studies have been conducted mostly in Caucasians .…”

Section: Introductionmentioning

confidence: 99%

Low prevalence of knee chondrocalcinosis and its catabolic association with serum matrix metalloproteinase 3: A rural Japanese population study

et al. 2017

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Does Chondrocalcinosis Affect Knee Society Scores and Range of Motion After TKA?

Abstract: Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

Cited by 9 publications

References 16 publications

Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review

Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review

The Incidence and Significance of Calcium Pyrophosphate Dihydrate Deposits in Histologic Examinations of Total Hip, Knee, and Shoulder Joint Arthroplasties

Low prevalence of knee chondrocalcinosis and its catabolic association with serum matrix metalloproteinase 3: A rural Japanese population study

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