Does changing paternity contribute to the risk of intrauterine growth retardation?

Krulewitch, Cara J.; Yu, Kai; Johnson, Yvette R.

doi:10.1046/j.1365-3016.11.s1.7.x

Cited by 14 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[10][11][12][13][14][15][16][17] We have only found one earlier study of SGA recurrence after partner change and this study could not show a protective effect of partner change. 18 This study was of a much smaller sample size than our study and did not control for several important confounders.…”

Section: Discussionmentioning

confidence: 68%

“…[10][11][12] Studies on the effect of partner change on risks of preeclampsia and intrauterine growth restriction in women without prior corresponding complication have yielded diverging results. [10][11][12][13][14][15][16][17][18] Reasons for this could be failure to separate out diseases associated with abnormal placentation, and that most earlier studies in this field lack control of important confounders. 10-12 14-18 We conducted a nationwide Swedish study and included a cohort of 446 000 women with their first and second births during the years 1990-2006 with available information on important factors influencing pregnancy outcomes.…”

Section: Key Messagesmentioning

confidence: 99%

See 1 more Smart Citation

The paternal role in pre-eclampsia and giving birth to a small for gestational age infant; a population-based cohort study

2012

View full text Add to dashboard Cite

ObjectiveTo estimate the effect of partner change on risks of pre-eclampsia and giving birth to a small for gestational age infant.DesignProspective population study.SettingSweden.ParticipantsWomen with their first and second successive singleton births in Sweden between 1990 and 2006 without pregestational diabetes and/or hypertension (n=446 459).Outcome measuresPreterm (<37 weeks) and term (≥37 weeks) pre-eclampsia, and giving birth to a small for gestational age (SGA) infant. Risks were adjusted for interpregnancy interval, maternal age, body mass index, height and smoking habits in second pregnancy, years of involuntary childlessness before second pregnancy, mother's country of birth, years of formal education and year of birth. Further, when we calculated risks of SGA we restricted the study population to women with non-pre-eclamptic pregnancies.ResultsIn women who had a preterm pre-eclampsia in first pregnancy, partner change was associated with a strong protective effect for preterm pre-eclampsia recurrence (OR 0.24; 95% CI 0.07 to 0.88). Similarly, partner change was also associated with a protective effect of recurrence of SGA birth (OR 0.75; 95% CI 0.67 to 0.84). In contrast, among women without SGA in first birth, partner change was associated with an increased risk of SGA in second pregnancy. Risks of term pre-eclampsia were not affected by partner change.ConclusionsThere is a paternal effect on risks of preterm pre-eclampsia and giving birth to an SGA infant.

show abstract

Section: Discussionmentioning

confidence: 68%

Section: Key Messagesmentioning

confidence: 99%

The paternal role in pre-eclampsia and giving birth to a small for gestational age infant; a population-based cohort study

2012

View full text Add to dashboard Cite

show abstract

“…Finally, maternally linked data are increasingly being used for follow-up studies, including studying recurrence of perinatal outcomes (6, 9, 10, 12, 13, 35, 36). Differences in recurrence by Hispanic ethnicity have not been studied to date, but this is a logical next step in this emerging area of research (37).…”

Section: Discussionmentioning

confidence: 99%

U.S. Maternally Linked Birth Records May Be Biased for Hispanics and Other Population Groups

Leiss¹,

Giles

Sullivan³

et al. 2010

Annals of Epidemiology

View full text Add to dashboard Cite

Purpose-To advance understanding of linkage error in U.S. maternally linked datasets, and how the error may affect results of studies based on the linked data.Methods-North Carolina birth and fetal death records for 1988-1997 were maternally linked (n=1,030,029). The maternal set probability, defined as the probability that all records assigned to the same maternal set do in fact represent events to the same woman, was used to assess differential maternal linkage error across race/ethnic groups.Results-Maternal set probabilities were lower for records specifying Asian or Hispanic race/ ethnicity, suggesting greater maternal linkage error. The lower probabilities for Hispanics were concentrated in women of Mexican origin who were not born in the United States.Conclusions-Differential maternal linkage error may be a source of bias in studies using U.S. maternally linked datasets to make comparisons between Hispanics and other groups or among Hispanic subgroups. Methods to quantify and adjust for this potential bias are needed.

show abstract

“…In addition to preeclampsia, a number of other adverse pregnancy outcomes have been associated with change in paternity, including reduced placental weight, reduced birth weight [Warburton and Naylor, 1971], intrauterine growth restriction [Krulewitch et al, 1997; Kleijer et al, 2005] birth weight less than 2,500 g, and preterm delivery [Li, 1999; Vatten and Skjaerven, 2003], supporting the hypothesis that maternal lack of immune tolerance to new paternal antigen may present challenges to the developing embryo or fetus.…”

Section: Introductionmentioning

confidence: 99%

Novel risk factor in gastroschisis: Change of paternity

Chambers

Chen

Kalla

et al. 2006

American J of Med Genetics Pt A

View full text Add to dashboard Cite

In recent years, an increase in the rate of gastroschisis has been documented in several countries throughout the world. Based on accumulating evidence that a maternal immunologic response to a novel set of paternal antigens may be involved in risk for several adverse pregnancy outcomes, including preeclampsia, reduced birth weight, and preterm delivery, we tested the hypothesis that a pregnancy following a change in fathers (change in paternity) may be a risk factor for gastroschisis. Using a case-control design, we compared the prevalence of change in paternity with the index pregnancy in 102 mothers of isolated gastroschisis cases to the prevalence of change in paternity in 117 mothers of non-malformed infants and 78 mothers of infants with neural tube defects or oral clefts. In a multivariate analysis, the adjusted odds of change in paternity in multigravid case mothers were 7.81 times higher (95% Confidence interval 2.80-21.88) relative to multigravid mothers of malformed and non-malformed controls combined, after adjustment for maternal age. These data suggest that maternal immune factors may play a role in the cause of gastroschisis. Further research is needed to corroborate these findings and to elucidate possible immunologic mechanisms involved in the pathogenesis of gastroschisis.

show abstract

Does changing paternity contribute to the risk of intrauterine growth retardation?

Cited by 14 publications

References 17 publications

The paternal role in pre-eclampsia and giving birth to a small for gestational age infant; a population-based cohort study

The paternal role in pre-eclampsia and giving birth to a small for gestational age infant; a population-based cohort study

U.S. Maternally Linked Birth Records May Be Biased for Hispanics and Other Population Groups

Novel risk factor in gastroschisis: Change of paternity

Contact Info

Product

Resources

About