“…Notably, in the general population, cannabis use is associated with cognitive deficits and health-related issues [ 16 , 17 , 18 ]. In addition to these effects, cannabis use in individuals with SMD also leads to decreased medication compliance, higher rates of hospitalization, poorer quality of life, and higher risk of auto- and hetero-aggressive violence [ 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ]. Studies have also shown that its use can lead to the exacerbation of psychiatric symptoms such as delusions and hallucinations, as well as precipitating or aggravating episodes of mania and depression [ 12 , 27 , 28 , 29 ].…”