Does body weight influence outcome after total knee arthroplasty? A 1-year analysis

Deshmukh, R. G.; Hayes, Jane Huffman; Pinder, I. M.

doi:10.1054/arth.2002.30776

Cited by 108 publications

(89 citation statements)

References 17 publications

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“…In this section we summarise results from 22 studies of pre-operative BMI, mental health, pain and physical function as predictors of long-term patient-reported outcomes. 46,50,127,[147][148][149][150][151][152][153][154][155][156][157][158][159][160][161][162][163][164][165] One study included important data in a second publication. 166 Details of studies are summarised in Appendix 6 with brief details in Table 5.…”

Section: Total Knee Replacementmentioning

confidence: 99%

“…46,160,161 Outcomes reported were SF-36 domains or the Nottingham Health Profile (NHP). 161 reported a UK study with 139 patients (77% eligible) treated by a single surgeon with follow-up at 12 months. In this study, the mean BMI was 28 kg/m 2 (SD 4.5 kg/m 2 ) and only two patients initially eligible had a BMI of ≥ 40 kg/m 2 .…”

Section: Body Mass Index As a Predictor Of General Health Outcomesmentioning

confidence: 99%

“…46,127,147,149,[151][152][153][154][155][159][160][161][162] Details of these studies are summarised in Table 5. As a marker of generalisability, one study reported a registry analysis, 147 eight studies included multiple centres, 46,127,149,[151][152][153][154][155] and four studies included patients from a single centre.…”

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confidence: 99%

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Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Blom

Artz

Beswick

et al. 2016

Programme Grants Appl Res

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms PROGRAMME GRANTS FOR APPLIED RESEARCH VOLUME 4 ISSUE 12 AUGUST 2016 ISSN 2050 DOI 10.3310/pgfar04120Improving patients' experience and outcome of total joint replacement: the RESTORE programme Ashley W Blom, Neil Artz, Andrew D Beswick, Amanda Burston, Paul Dieppe, Karen T Elvers, Rachael Gooberman-Hill, Jeremy Horwood, Paul Jepson, Emma Johnson, Erik Lenguerrand, Elsa Marques, Sian Noble, Mark Pyke, Catherine Sackley, Gina Sands, Adrian Sayers, Victoria Wells and Vikki Wylde Improving patients' experience and outcome of total joint replacement: the RESTORE programme ISSN 2050-4330 (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full PGfAR archive is freely available to view online at www.journalslibrary.nihr.ac.uk/pgfar. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Programme Grants for Applied Research journalReports are published in Programme Grants for Applied Research (PGfAR) if (1) they have resulted from work for the PGfAR programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. Programme Grants for Applied Research programmeThe Programme Grants for Applied Research (PGfAR) programme, part of the National Institute for Health Research (NIHR), was set up in 2006 to produce independent research findings that will have practical application for the benefit of patients and the NHS in the relatively near future. The Programme is managed by the NIHR Central Commissioning Facility (CCF) with strategic input from the Programme Director.The programme is a national response mode funding scheme that aims to provide evidence to improve health outcomes in England through promotion of health, prevention of ill health, and optimal disease management (including safety and quality), with particular emphasis on conditions causing significant disease burden.For more information about the PGfAR programme please visit the website: http://www.nihr.ac.uk/funding/programme-grants-forapplied-research.htm This reportThe research reported in this issue of the journal was funded by PGfAR as project number RP-PG-0407-10070. The contractual start date was in December 2008. The final report began editorial review in September 2014 and was accepted for publication in August 2015. As the funder, the PGfAR programme agreed the research questions and study designs in advance with the investigators. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The PGfAR editors and production house have tried to ensure the accurac...

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Section: Total Knee Replacementmentioning

confidence: 99%

Section: Body Mass Index As a Predictor Of General Health Outcomesmentioning

confidence: 99%

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Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Blom

Artz

Beswick

et al. 2016

Programme Grants Appl Res

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“…According to Bourne et al [4], the Canadian Joint Replacement Registry showed an 8.56-fold increased risk for a patient with class III obesity (BMI[40 kg/m 2 ) to undergo a total hip replacement. There is controversy regarding whether obesity poses additional complications and costs with THA [7,20,28]. Some studies have reported that the risk of postoperative complications after joint arthroplasty in patients who are obese is comparable to the risk in patients who are nonobese as long as their BMI is less than 40 kg/m 2 [1,17].…”

Section: Introductionmentioning

confidence: 99%

Surgical Risks and Costs of Care are Greater in Patients Who Are Super Obese and Undergoing THA

Meller¹,

Toossi

Gonzalez

et al. 2016

Clinical Orthopaedics &Amp; Related Research

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Background Patients with morbid obesity, defined as a BMI greater than 40 kg/m 2 , and super obesity, defined as a BMI greater than 50 kg/m 2 , increasingly present for total hip replacement. There is disagreement in the literature whether these individuals have greater surgical risks and costs for the episode of care, and the magnitude of those risks and costs. There also is no established threshold for obesity as defined by BMI in identifying increased complications, risks, and costs of care. Until recently, analysis of higher BMI data was limited to small cohorts from hospital-based data banks, based on BMI or height and weight only, often as part of a multivariate analysis. On October 1, 2010 the Centers for Medicare & Medicaid Services added a fifth digit to the BMI data, V85.xx, in the Medicare data bank, which allowed data mining of cases of patients with higher BMI. To our knowledge, our study is the first large retrospective Medicare data mining study, which allows us to examine BMI levels greater than 40 and 50 kg/m 2 to delineate risks, complications, and costs for these patients. Questions/purposes We sought to quantify (1) the surgical risk, and (2) the costs associated with complications after THA in patients who were morbidly obesity (BMI C 40 kg/m 2 ) or super obese (BMI C 50 kg/m 2 ). Methods This is a retrospective study of patients, using Medicare hospital claims data, who underwent THA. The ICD-9 Clinical Modification (CM) diagnosis code V85.4x was used to identify patients with morbid obesity and with super obesity from October 1, 2010 through December 31, 2014. Patients without any BMI-related diagnosis codes were used as the control group. Twelve complications occurring during the 90 days after THA were analyzed using multivariate Cox models adjusting for patient demographic, comorbidities, and institutional factors. In addition, hospital charges and payments were compared from primary surgery through the subsequent 90 days.Each author certifies that he or she, or a member of his or her immediate family, has no funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article. All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research 1 editors and board members are on file with the publication and can be viewed on request. Each author certifies that his or her institution approved or waived approval for the human protocol for this investigation and that all investigations were conducted in conformity with ethical principles of research. This study was performed via electronic collaboration at the authors' institutions. (HR, 3.91; 95% CI, 3.14-4.86; p \ 0.001). In addition, patients with morbid obesity had increased risk of deep vein thrombosis (HR, 1.43; 95% CI, 1.14-1.79; p \ 0.002), pulmonary embolism (HR, 1.57; 95% CI, 1.25-1.99; p \ 0.001), implant failure (HR, 1.48; 95% CI, 1.3-1.68; p \ 0.001), acute ...

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“…[2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Obesity/ BMI/body weight was not adversely associated with post-TKA functional outcome at 1, 3, 6, and 12 months, 4,7,12 pain outcome at 2 and 5 years, 8 Hospital for Special Surgery score, 2 or Knee Society Score, Western Ontario and McMaster Universities Arthritis Index, and Short Form-12 Health Survey score at 9.5 years. 5 Obese and morbidly obese patients were reported to gain as much functional benefit (and relief of symptoms 16 ) from TKA as other patients at 3 years.…”

Section: Reviewmentioning

confidence: 99%

Review Article: Outcome of Total Knee Arthroplasty in Obese Patients

Rodríguez-Merchán

2015

J Orthop Surg (Hong Kong)

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The MEDLINE database was searched using the key words: 'obesity' and 'knee arthroplasty'. 41 articles focused on the topic were reviewed; most studies were prospective case series (providing low-level evidence) and 3 were systematic reviews. 16 studies reported no adverse association between obesity and total knee arthroplasty (TKA) outcome, whereas 24 studies reported a poorer TKA outcome in obese patients. In the 3 systematic reviews, obesity was reported to adversely affect the outcome, the rate of complications, implant survival, and the cost of TKA.

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Does body weight influence outcome after total knee arthroplasty? A 1-year analysis

Cited by 108 publications

References 17 publications

Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Surgical Risks and Costs of Care are Greater in Patients Who Are Super Obese and Undergoing THA

Review Article: Outcome of Total Knee Arthroplasty in Obese Patients

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