Does alcohol influence the cognitive functions of schizophrenic patients?

Buleyko, A A; Soldatkin, V.A.; Murina, I V; Ruban, D A; Simak, Olga Ya; Krysenko, P B; Kryuchkova, M. N.

doi:10.17116/jnevro201911907114

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…Most studies investigating the cognitive impact of alcohol in schizophrenia patients with comorbid AUD revealed a negative association between alcohol use and cognitive function [ 6 , 7 , 43 , 44 , 45 , 46 ]. On the contrary, some studies have suggested that AUD has no additive effects on cognitive impairment in schizophrenia patients [ 47 , 48 , 49 ] or has positive associations with social cognition [ 50 , 51 , 52 , 53 ], task-making, and the speed processing domains [ 54 ].…”

Section: Discussionmentioning

confidence: 99%

Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder

et al. 2021

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The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia, and schizoaffective disorder and alcohol use might aggravate this phenomenon. The study population included 3362 individuals from Finland with diagnoses of schizophrenia or schizoaffective disorder. Hazardous drinking was screened with the AUDIT-C (Alcohol Use Disorders Identification Test for Consumption) screening tool. Alcohol use disorder (AUD) diagnoses were obtained from national registrar data. Participants performed two computerized tasks from the Cambridge Automated Neuropsychological Test Battery (CANTAB) on a tablet computer: The Five-Choice Serial Reaction Time Task (5-CSRTT) or the reaction time (RT) test and the Paired Associative Learning (PAL) test. The association between alcohol use and the RT and PAL tests was analyzed with log-linear regression and logistic regression, respectively. After adjustment for age, education, housing status, and the age at which the respondents had their first psychotic episodes, hazardous drinking was associated with a lower median RT in females and less variable RT in males, while AUD was associated with a poorer PAL test performance in terms of the total errors adjusted scores (TEASs) in females. Our findings of positive associations between alcohol and cognition in schizophrenia and schizoaffective disorder are unique.

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Section: Discussionmentioning

confidence: 99%

Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder

et al. 2021

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“…Most studies investigating cognitive impact of alcohol in schizophrenia patients with comorbid AUD revealed negative association between alcohol use and cognitive function [6,7,49,50,51,52]. On the other hand, some studies suggested that AUD had no additive effects on cognitive impairment in schizophrenia patients [53,54,55], or had positive associations with social cognition [56,57,58,59], task making and the speed processing domains [60].…”

Section: Comparison With Other Studiesmentioning

confidence: 99%

Reaction Time and Visual Memory in Connection to Alcohol Use In Schizophrenia and Schizoaffective Disorder

Mazumder¹,

Barnett²,

Lindberg³

et al. 2021

Preprint

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Purpose of the study was to explore the association of cognition with hazardous drinking, binge drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognitive deficits are common in schizophrenia. Alcohol might be associated with additional cognitive impairment in schizophrenia patients. The study population included 3362 schizophrenia and schizoaffective disorder patients in Finland. Hazardous drinking was screened with the AUDIT-C (Alcohol Use Disorders Identification Test for Consumption) screening tool. Binge drinking was obtained from the AUDIT-C. Alcohol use disorder (AUD) diagnoses were obtained from the national registrar data. Participants performed two computerized tasks from the Cambridge automated neuropsychological test battery (CANTAB) on tablet computer: the 5-choice serial reaction time task (5-CSRTT), or, reaction time (RT) test and the Paired Associative Learning (PAL) test. Association of alcohol use with RT test and PAL test was analyzed with log-linear regression and logistic regression, respectively. After adjustment for age, education and age at first psychotic episode, hazardous drinking in females was associated with lower median RT. Compared to never binge drinkers, male and female participants drinking 6 or more doses of alcohol monthly or less had lower median RT. In the PAL test both first trial memory score (FTMS) and total errors adjusted score (TEAS) were associated with better performance in males drinking 6 or more doses of alcohol weekly or more and in females drinking 6 or more doses monthly or less. Higher PAL TEAS was associated with AUD in females Some positive associations between alcohol and cognition were found in male and female schizophrenia and schizoaffective disorder patients with hazardous drinking and binge drinking.

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Features of cognitive impairment in individuals with paranoid schizophrenia combined with alcohol dependence syndrome

Толмачева¹,

Kiseleva²,

Chernov³

et al. 2021

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Does alcohol influence the cognitive functions of schizophrenic patients?

Cited by 4 publications

References 21 publications

Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder

Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder

Reaction Time and Visual Memory in Connection to Alcohol Use In Schizophrenia and Schizoaffective Disorder

Features of cognitive impairment in individuals with paranoid schizophrenia combined with alcohol dependence syndrome

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