Does abnormal ductus venosus pulsatility index at the first-trimester effect on adverse pregnancy outcomes?

Baran, Şafak Yılmaz; Kalaycı, Hakan; Durdağ, Gülşen Doğan; Yetkinel, Selçuk; Arslan, Alev

doi:10.1016/j.jogoh.2020.101851

Cited by 6 publications

(7 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, in the case of fetuses with a heart defect, the venous flow rate through the DV was approximately 1.25 m/s, whereas in healthy fetuses, the DV-PI was at a level no higher than 1.0 m/s. Similar observations were noted by Baran et al [ 47 ], who reported that fetuses with developmental anomalies had an average DV-PI value of 1.22 m/s [ 47 ]. Additionally, in one of the cohort examinations regarding DV-PI reference values, it was indicated to interpret venous flow rates below 0.93 m/s and above 1.22 m/s as abnormal [ 48 ], which is compatible with our observations in this study.…”

Section: Discussionsupporting

confidence: 88%

Risk Assessment of the Increased Occurrence of Congenital Cardiac and Non-Cardiac Defects in Fetuses with a Normal Karyotype after Assisted Fertilization in Comparison to Natural Fertilization Based on Ultrasound Diagnostics

Serafin¹,

Grabarek²,

Boroń³

et al. 2021

JCM

View full text Add to dashboard Cite

The goal of the study was to assess changes in parameters based on ultrasound examinations—these were Crown Rump Length (CRL), Nuchal Translucency (NT), Fetal Heart Rate (FHR), and Pulsatility Index for Ductus Venosus (DV-PI)—in the first trimester of pregnancy in women in which there was a natural initiation of the pregnancy due to spontaneous ovulation, women in which the pregnancy was initiated as a result of stimulated ovulation, as well as in the group in which pregnancy was achieved through the use of In-Vitro Fertilization (IVF)-assisted reproduction. A total of 1581 women became pregnant without the use of assisted reproduction methods. Out of 283 pregnancies, in 178 patients, induced ovulation was utilized. Next, 137 women had sexual intercourse and became pregnant; 41 of them became pregnant through Intrauterine Insemination (IUI) as a result of Artificial Insemination by Husband (AIH), and 13 became pregnant after Artificial Insemination by Donor (AID). The third group consisted of 105 women subjected to Controlled Ovarian Hyperstimulation (COH). In this group of pregnant women, 53 pregnancies were resultant of Intracytoplasmic Sperm Injection (ICSI), and 52 pregnancies were the result of Intracytoplasmic Morphologically selected Sperm Injection (IMSI). The obtained results did not indicate that the chosen method of fertilization or the chosen ovulation method had a statistically significant effect on the development risk of congenital heart or non-heart defects in the fetus.

show abstract

Section: Discussionsupporting

confidence: 88%

Risk Assessment of the Increased Occurrence of Congenital Cardiac and Non-Cardiac Defects in Fetuses with a Normal Karyotype after Assisted Fertilization in Comparison to Natural Fertilization Based on Ultrasound Diagnostics

Serafin¹,

Grabarek²,

Boroń³

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…During this investigation, DV-PI was identified as an important predictive feature of FGR, and its inclusion improved the discrimination of several models. DV-PI was elevated in pregnancies with FGR, which is consistent with findings from the mid-to-third trimester 10 .…”

Section: Discussionsupporting

confidence: 87%

“…The ductus venosus (DV) connects the umbilical vein to the fetal inferior vena cava, and plays a crucial role in fetal growth and development. The DV-PI and peak systolic velocity (PSV) have been associated with adverse pregnancy outcome, including FGR 9,10 .…”

Section: Introductionmentioning

confidence: 99%

Construction of prediction model for fetal growth restriction during first trimester in an Asian population

Zheng,

Ji,

Wang

et al. 2024

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

ObjectiveTo construct a prediction model for fetal growth restriction (FGR) during the first trimester (11‐13+6 weeks) and evaluate its screening performance.MethodsSingle pregnancies who underwent the first trimester (11‐13+6 weeks) ultrasound screening at the Affiliated Suzhou Hospital of Nanjing Medical University from January 2019 to April 2022 were selected as prospective study subjects. Basic clinical information, ultrasound indicators, and serum indicators of pregnant women were collected. Fetal weight assessment was based on the fetal growth curve of the Southern Chinese population, and the definition of FGR was based on standards developed through the Delphi process. The least absolute shrinkage and selection operator (LASSO) regression method was used to select optimal features and analyze the predictive value of each indicator in the model. Finally, the model was constructed, and its discrimination, effectiveness, and clinical usefulness were evaluated.ResultsA total of 1188 pregnant women were included in the final statistical analysis, of whom 108 had FGR. LASSO regression identified 7 predictive features, including a history of maternal hypertension, maternal smoking or passive smoking history, number of pregnancies, uterine artery pulsatility index (UtA PI), ductus venosus pulsatility index (DV PIV), placental growth factor multiples of the median (PlGF MOM), and soluble fms‐like tyrosine kinase‐1 (sFlt‐1) MOM. The nomogram prediction model constructed based on the above predictors predicted FGR more accurately, and the area under the curve (AUC) in the validation cohort was 0.82 (95%CI: 0.74‐0.90). The calibration curve and Hosmer‐Lemeshow test demonstrated good calibration of the model, while the clinical decision curve and clinical impact curve conclusively support its practical value in the clinical setting.ConclusionThe multi‐index prediction model constructed during the first trimester is feasible and has good predictive value.This article is protected by copyright. All rights reserved.

show abstract

“…In this regard, several studies evaluated the diagnostic value of DV blood ow in detecting chromosomal abnormalities, congenital heart disease and adverse pregnancy outcomes [3][4][5][6]. As a result, the value of some parameters such as DVPI has been the topic of ongoing discussion in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Abnormal DV waveform (reversal or absence of A-wave) in the rst trimester of pregnancy is associated with chromosomal abnormality, congenital heart defects, and adverse pregnancy outcomes [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Reference values for Ductus Venosus pulsatility index between 11 and 13 + 6 weeks of Gestation: A Single-center Observational Study in a Tertiary Care Hospital

Hajiahmadi

Adariani

Amini

2021

Preprint

View full text Add to dashboard Cite

BackgroundThe ductus venosus pulsatility index(DVPI) has been evolved as an important marker of the first trimester screening sonography. The aim of this study is to define a reference for ductus venosus pulsatility index at 11–13 +6 weeks of gestation.MethodsIn this cross sectional observational study, 415 women with singleton pregnancies and crown lump length(CRL) between 45 and 84 mm were included. Exclusion criteria were abnormal biochemical screening results, presence of fetal structural malformation or chromosomal abnormalities such as thickened nuchal fold, abnormal perinatal outcomes, and newborns with a chromosomal abnormality. Transabdominal U/S was performed in all participants by an expert radiologist in obstetric sonography. CRL, nuchal translucency(NT), and blood flow indices of ductus venosus (DV) in each fetus were measured. The collected data were analyzed by IBM SPSS software version 20. Linear regression was performed to demonstrate the association between CRL DVPI. Further, 5th, 50th, and 95th percentiles of DV blood flow indices were calculated for each gestational age.ResultThe mean value of DVPI ranged from 1.05 at CRL 42mm to 1.3 at CRL 82mm. DVPI and CRL did not show any significant linear association (Regression coefficient B=0.001, R2=0.003, P=0.31)Conclusion: We defined means and ranges of DVPI, while determining the 5th, 50th, and 95th percentiles of DVPI for each CRL at our institution which were approximately similar to previous studies.

show abstract

Does abnormal ductus venosus pulsatility index at the first-trimester effect on adverse pregnancy outcomes?

Cited by 6 publications

References 27 publications

Risk Assessment of the Increased Occurrence of Congenital Cardiac and Non-Cardiac Defects in Fetuses with a Normal Karyotype after Assisted Fertilization in Comparison to Natural Fertilization Based on Ultrasound Diagnostics

Risk Assessment of the Increased Occurrence of Congenital Cardiac and Non-Cardiac Defects in Fetuses with a Normal Karyotype after Assisted Fertilization in Comparison to Natural Fertilization Based on Ultrasound Diagnostics

Construction of prediction model for fetal growth restriction during first trimester in an Asian population

Reference values for Ductus Venosus pulsatility index between 11 and 13 + 6 weeks of Gestation: A Single-center Observational Study in a Tertiary Care Hospital

Contact Info

Product

Resources

About