“…2,8,9,12 Common clinical signs include dermatitis with variable pruritus and alopecia, conjunctivitis, catarrhal or serous rhinitis, weight loss, fever, reduced milk production, diarrhea, lymphadenopathy, weakness, tachypnea and tachycardia. 2,4,[7][8][9]12,13 Histopathology shows disseminated granulomatous inflammation characterized by infiltrates of macrophages, lymphocytes, and plasma cells with variable numbers of multinucleated giant cells and eosinophils. 1,2,[7][8][9]11,13,15 Lesions can be seen in any organ; however, the main organs affected include skin, kidney, adrenal gland, lymphoid tissues, heart, liver and thyroid glands.…”