Documented Pain Diagnoses in Adults Prescribed Opioids: Results From the National Ambulatory Medical Care Survey, 2006–2015

Sherry, Tisamarie B.; Sabety, Adrienne; Maestas, Nicole

doi:10.7326/m18-0644

Cited by 27 publications

(24 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…31 CNS drug-drug interactions with opioids, even when prescribed for a short period of time, deserve clinical attention by pharmacists and other practitioners able to perform comprehensive medication reconciliation. 32 The greater prevalence of CNS-active medication use increases the likelihood that incidental coprescribing of CNS-active drugs will occur with opioids prescribed for acute pain management, including in dental settings. Our findings affirm the Beers Criteria update in 2019 that indicate that even a short days' supply or opportunity for drug-drug interaction carries significantly increased risk for acute care utilization.…”

Section: Discussionmentioning

confidence: 99%

Potentially Inappropriate Medication Combination with Opioids among Older Dental Patients: A Retrospective Review of Insurance Claims Data

et al. 2020

View full text Add to dashboard Cite

BACKGROUND Opioid prescribing by dentists for older patients receiving medications with potential contraindications and the subsequent impact on acute care outcomes is not well described. OBJECTIVES Our objective of this paper was to evaluate the use of potentially inappropriate medication combinations (PIMCs) involving opioids prescribed by dentists according to the Beers Criteria and risks of 30-day emergency department (ED) visits and all-cause hospitalization among commercially insured dental patients ages 65 years and older. METHODS We conducted a retrospective cohort study of 40,800 older dental patient visits in which opioids were prescribed between 2011 and 2015 using the IBM MarketScan databases. Data collection from dental, medical, and pharmacy claims included information on the concurrent use of PIMCs and outcomes of all-cause acute care utilization over the 30-day period after dental encounters. RESULTS For the overall cohort, the median age was 69 years, and 45% were women. The prevalence of PIMCs per Beers Criteria was 10.4%. A total of 947 all-cause acute care events were observed in the 30 days post-dental visit. Patients with PIMCs involving opioids prescribed by dentists according to the Beers Criteria had higher rates of acute care use (3.3% vs 2.2%, p<0.001), which were associated with an increased risk of all-cause acute care utilization (adjusted risk ratio [RR] 1.23, 95% confidence interval [CI] 1.02-1.48). A dose-response relationship was seen with increasing oral morphine equivalents prescribed and increased acute care utilization (p<0.001).

show abstract

Section: Discussionmentioning

confidence: 99%

Potentially Inappropriate Medication Combination with Opioids among Older Dental Patients: A Retrospective Review of Insurance Claims Data

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Participants could have more than 1 reason for opioid use if they had multiple prescriptions or if a single prescription was linked to multiple conditions. All reported ICD-9 codes were classified using a typology adapted from Sherry and colleagues 42 and listed in Appendix Table 2, available online.…”

Section: Methodsmentioning

confidence: 99%

Obesity and Incident Prescription Opioid Use in the U.S., 2000–2015

Stokes

Lundberg

Hempstead

et al. 2020

American Journal of Preventive Medicine

View full text Add to dashboard Cite

Introduction: Prior studies have identified associations between obesity and numerous conditions that increase risks for chronic pain. However, the impact of obesity on prescription opioid use is not well known. This study investigates the association between obesity and incidence of long-term prescription opioid use.Methods: Fifteen panels of the Medical Expenditure Panel Survey from 2000 to 2015 were pooled to generate a sample of civilian non-institutionalized adults aged 30−84 years who were prescription opioid−naïve for approximately 9 months. Incident long-term prescription opioid use was defined as reporting use at 2 of 3 interviews during a 15-month follow-up. BMI was reported at baseline. Analyses were completed in 2019.Results: Among opioid−naïve adults (n=89,629), obesity was strongly associated with incident long-term prescription opioid use. The association increased at progressively higher BMI values, with 24% elevated odds (95% CI=7%, 44%) in adults with overweight (25−29.9 kg/m 2 ) and 158% increased odds (95% CI=106%, 224%) among adults with Class III obesity (40−49.9 kg/m 2 ). These associations grew with higher-dosage opioids. Of the reasons for opioid use, joint pain, back pain, injury, and muscle/nerve pain contributed the most to the excess use observed among adults with obesity. At the population level, 27.0% of incident long-term prescription opioid use (95% CI=19.0%, 34.8%) was attributable to adults having a BMI above normal weight (25−49.9 kg/m 2 ). Conclusions:These findings suggest that obesity has contributed to prescription opioid use in the U.S. Future investments in chronic pain reduction may benefit from increased integration with obesity prevention and treatment. Am J Prev Med 2020;58(6):766−775.

show abstract

“…25 Other covariates included age (35-39, 40-44, 45-49, 50-54, 55-59, and 60-64 years), sex (male, female), race/ethnicity (non-Hispanic white, non-Hispanic black, Hispanic, non-Hispanic other), census region (Northeast, Midwest, South, and West), urbanicity (metropolitan, metroadjacent, and rural), and health insurance (commercial, Medicaid, Medicare, and other). We used a typologic system developed by Sherry et al 26 We documented whether patients received prescription opioids for management of each of the 25 diagnoses. Patients could have more than 1 diagnosis if they had multiple claims in the 7 days before an opioid prescription or if they had multiple prescriptions.…”

Section: Study Design and Measuresmentioning

confidence: 99%

Association of Obesity With Prescription Opioids for Painful Conditions in Patients Seeking Primary Care in the US

et al. 2020

View full text Add to dashboard Cite

IMPORTANCE Prior studies have identified an association between obesity and prescription opioid use in the US. However, the pain conditions that are factors in this association remain unestablished. OBJECTIVE To investigate the association between obesity and pain diagnoses recorded by primary care clinicians as reasons for prescription of opioids. DESIGN, SETTING, AND PARTICIPANTS A cross-sectional study including 565 930 patients aged 35 to 64 years with a body mass index (BMI) measurement recorded in 2016 was conducted.

show abstract

Documented Pain Diagnoses in Adults Prescribed Opioids: Results From the National Ambulatory Medical Care Survey, 2006–2015

Cited by 27 publications

References 4 publications

Potentially Inappropriate Medication Combination with Opioids among Older Dental Patients: A Retrospective Review of Insurance Claims Data

Potentially Inappropriate Medication Combination with Opioids among Older Dental Patients: A Retrospective Review of Insurance Claims Data

Obesity and Incident Prescription Opioid Use in the U.S., 2000–2015

Association of Obesity With Prescription Opioids for Painful Conditions in Patients Seeking Primary Care in the US

Contact Info

Product

Resources

About