Documentation and Evaluation of Cognitive Impairment in Elderly Primary Care Patients

Callahan, Christopher M.; Hendrie, Hugh C.; Tierney, William M.

doi:10.7326/0003-4819-122-6-199503150-00004

Cited by 456 publications

(365 citation statements)

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“…Unlike Sands et al (21), we did not pay specific attention to cognitively impaired subjects and did not observe patients with severe cognitive impairment as those authors did, but our data did not show a relationship between cognitive functions and functional decline (25,26). We could speculate by saying that, in very old patients, normal or moderate mental status does not affect functional decline during hospitalization, but the low sample number does not permit any generalization.…”

Section: © 2 0 0 9 E D I T R I C E K U R T I S F O R P E R S O N a contrasting

confidence: 90%

Risk factors of functional decline during hospitalization in the oldest old

et al. 2009

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Section: © 2 0 0 9 E D I T R I C E K U R T I S F O R P E R S O N a contrasting

confidence: 90%

Risk factors of functional decline during hospitalization in the oldest old

et al. 2009

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“…A major cause of abnormal cognitive aging is Alzheimer disease (AD) which, in its initial stages, is characterized clinically by impairment in declarative memory and neuropathologically by intracellular deposits of tau, in the form of neurofibrillary tangles, extracellular deposits of beta-amyloid, and neuronal loss in the medial temporal lobe including the hippocampus and entorhinal cortex. AD is a slowly progressive process and the transition between normal aging and the earliest stages of AD is difficult to discern by most routine medical evaluations (Callahan et al, 1995;Ganguli et al, 2004b).…”

Section: Introductionmentioning

confidence: 99%

Effect of memory impairment on training outcomes in ACTIVE

Unverzagt

Kasten

Johnson

et al. 2007

J Int Neuropsychol Soc

109

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Cognitive training improves mental abilities in older adults, but the trainability of persons with memory impairment is unclear. We conducted a subgroup analysis of subjects in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial to examine this issue. ACTIVE enrolled 2802 non-demented, community-dwelling adults aged 65 years and older and randomly assigned them to one of four groups: Memory training, reasoning training, speed-of-processing training, or no-contact control. For this study, participants were defined as memory-impaired if baseline Rey Auditory Verbal Learning Test (AVLT) sum recall score was 1.5 SD or more below predicted AVLT sum recall score from a regression-derived formula using age, education, ethnicity, and vocabulary from all subjects at baseline. Assessments were taken at baseline (BL), post-test, first annual (A1), and second annual (A2) follow-up. One hundred and ninety-three subjects were defined as memory-impaired and 2580 were memory-normal. Training gain as a function memory status (impaired vs. normal) was compared in a mixed effects model. Results indicated that memoryimpaired participants failed to benefit from Memory training but did show normal training gains after reasoning and speed training. Memory function appears to mediate response to structured cognitive interventions in older adults.

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“…The A&D Consensus Group addressed the well-documented and widely recognized problem of inadequate recognition of dementia in clinical practice [2][3][4][5][6]. Freund [7] estimated that the missed diagnoses are greater than 25% of the dementia cases and might be as high as 90%.…”

Section: The Clinical Evidence Justifies Screening For Dementiamentioning

confidence: 99%

Should older adults be screened for dementia? It is important to screen for evidence of dementia!

Ashford

Borson

O’Hara

et al. 2007

Alzheimer's & Dementia

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Multiple arguments for considering routine dementia screening have been presented. Furthermore, dementia diagnoses are widely unrecognized. As a result, persons with dementia are missing important clinical care and treatment interventions. By distinction, the problems of defining, diagnosing, and treating mild cognitive impairment (MCI) are not yet resolved, and MCI is not ready for a screening recommendation. Dementia screening approaches, including cognitive testing and functional assessment, must be evaluated on their scientific merits, including sensitivity and

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Documentation and Evaluation of Cognitive Impairment in Elderly Primary Care Patients

Cited by 456 publications

References 0 publications

Risk factors of functional decline during hospitalization in the oldest old

Risk factors of functional decline during hospitalization in the oldest old

Effect of memory impairment on training outcomes in ACTIVE

Should older adults be screened for dementia? It is important to screen for evidence of dementia!

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