Docosahexaenoic Acid Explains the Unexplained in Visual Transduction
Michael A. Crawford,
Andrew J. Sinclair,
Yiqun Wang
et al.
Abstract:In George Wald’s Nobel Prize acceptance speech for “discoveries concerning the primary physiological and chemical visual processes in the eye”, he noted that events after the activation of rhodopsin are too slow to explain visual reception. Photoreceptor membrane phosphoglycerides contain near-saturation amounts of the omega-3 fatty acid docosahexaenoic acid (DHA). The visual response to a photon is a retinal cis–trans isomerization. The trans-state is lower in energy; hence, a quantum of energy is released eq… Show more
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