Computational science is a main pillar of most present research as well as industrial and commercial activities and it plays a unique role in exploiting ICT innovative technologies. The ICCSA conference series has been providing a venue to researchers and industry practitioners to discuss new ideas, to share complex problems and their solutions, and to shape new trends in computational science.Apart from the general tracks, ICCSA 2016 also included 33 international workshops, in various areas of computational sciences, ranging from computational science technologies to specific areas of computational sciences, such as computer graphics and virtual reality. The program also featured three keynote speeches and two tutorials.The success of the ICCSA conference series, in general, and ICCSA 2016, in particular, is due to the support of many people: authors, presenters, participants, keynote speakers, session chairs, Organizing Committee members, student volunteers, Program Committee members, Steering Committee members, and many people in other various roles. We would like to thank them all.