Dobutamine stress echocardiography for the detection of significant coronary artery disease in renal transplant candidates

Avaliação e manejo da doença cardiovascular em pacientes com doença renal crônica

“…11 For detecting CAD in dialysis patients, data currently available suggest that vasodilator-induced stress nuclear scintigraphy (adenosine or dipyridamole) is less sensitive than stress echocardiography. 12 Those data, however, derive from studies in diabetic patients being assessed for transplantation, and cannot be extrapolated to the entire dialysis population. Thus, very often, CKD patients on dialysis undergo coronary cineangiography for investigating CAD, since non invasive methods have no significant accuracy.…”

The Evaluation of the Renal Transplant Candidates: Clinical Practice Guidelines

“…Using a 70% occlusion cutpoint the sensitivity was 75% and the specificity 71% (701). For a 75% cutpoint by visual estimation, the sensitivity and specificity were 75% and 76%, respectively (701).…”

“…Dobutamine echocardiography has shown promise as a screening test for coronary artery disease in a number of investigations of non-ESRD patients (675,676) and ESRD patients being considered for renal transplantation (698)(699)(700)(701).…”

“…In one study the incidence of coronary artery disease (lesions of at least 50% occlusion) was 47%, the sensitivity 86%, the specificity 94%, the positive predictive value 92% and the negative predictive value 88% (698). In a study using 50% occlusion to define coronary artery disease (assessed by quantitative angiography) the sensitivity was 52% and the specificity 74% (701). Using a 70% occlusion cutpoint the sensitivity was 75% and the specificity 71% (701).…”

“…In a study using 50% occlusion to define coronary artery disease (assessed by quantitative angiography) the sensitivity was 52% and the specificity 74% (701). Using a 70% occlusion cutpoint the sensitivity was 75% and the specificity 71% (701). For a 75% cutpoint by visual estimation, the sensitivity and specificity were 75% and 76%, respectively (701).…”