Do total parenteral nutrition and bowel rest reduce the risk for perforation in patients with gastrointestinal tract lymphoma receiving chemotherapy?

Wong, Yu Jun; Lum, Huey-Ming; Fook‐Chong, Stephanie; Lim, Soon-Thye; Salazar, Ennaliza

doi:10.1016/j.nut.2019.03.023

Cited by 7 publications

(10 citation statements)

References 12 publications

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“…5-16, 20-25, 28-40, 42, 44, 46 Twelve (n=12) studies involved or investigated the use of EN and/or PN, 18, 22, 26, 28, 30-33, 35, 37, 38, 40 while the rest (n=32) involved nutritional screening and/or assessment. 5-17, 19-21, 23-25, 27, 29, 34, 36, 39, 41-46 Only two (n=2) studies were randomised controlled trials, 26,30 and the rest were retrospective 18,28,31,32,41,43,46 (n=7), prospective or cross-sectional 5-8, 10-17, 19-21, 23-25, 27, 29, 33-40, 42, 44, 45 (n=31), pre-post 22 (n=1) and validation 9 (n=1) studies. Nine (n=9) studies belong to the Singapore Longitudinal Ageing Studies 1 and 2 population.…”

Section: Resultsmentioning

confidence: 99%

“…More research is also required in the area of nutrition support. Only three observational studies on PN were identified within the past 20 years, 28,31,32 and more interventional and economic evaluation studies are necessary to determine the clinical and cost-effectiveness of using PN in a local context. There was also a limited number of EN studies, particularly in acute care settings.…”

Section: Discussionmentioning

confidence: 99%

“…28 There was, however, a significant change in C-reactive protein at day 5 between conventional and alternative IVLEs (8.43 ± 112.2 g/L vs. -41.2 ± 106.4 g/L, adjusted P=0.01). 28 Wong et al 32 investigated the effects of total parenteral nutrition (TPN) on perforation risk for gastrointestinal lymphoma. The authors compared patients on chemotherapy receiving TPN and bowel rest with those not receiving TPN and bowel rest.…”

Section: Oral Enteral and Parenteral Nutrition Supportmentioning

confidence: 99%

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Adult malnutrition, nutritional interventions and outcomes in Singapore: a scoping review of local studies for the past 20 years

Wong

Huang

Sowa

et al. 2020

Proceedings of Singapore Healthcare

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Background: There is currently no review published on the prevalence and incidence of malnutrition in Singapore across various populations, or what interventions or policies are in place for preventing/treating malnutrition. Objectives: This review aims to determine the: (a) incidence and prevalence of malnutrition in the community, and in acute, intermediate and long-term care facilities; (b) interventions implemented for screening, assessing and treating/preventing malnutrition; (c) specific clinical populations investigated for malnutrition or nutritional therapy; and (d) implications of malnutrition and effectiveness of treating malnutrition or using nutritional therapy in Singapore. Methods: A structured search strategy was applied to available electronic databases (MEDLINE/PubMed, EMBASE, CINAHL, the Cochrane Library and Google Scholar) using selected search terms, with additional reports and grey literature identified using iterative searches. Results: Forty-two articles were found, with the majority of research performed in the community and acute care settings. Malnutrition screening and assessment is the most common nutritional research performed in Singapore. Approximately 14.7% to 65.0% of acute care and 2.8% to 31.5% of community populations are found to be malnourished. Limited interventional and economic-related studies are available. Conclusion: Malnutrition rates in Singapore appear to be similar to other developed countries. Future studies will need to focus on nutritional intervention, cost-effectiveness analyses and specific populations such as the underprivileged, chronically ill and those dependent on nutritional support.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Oral Enteral and Parenteral Nutrition Supportmentioning

confidence: 99%

See 1 more Smart Citation

Adult malnutrition, nutritional interventions and outcomes in Singapore: a scoping review of local studies for the past 20 years

Wong

Huang

Sowa

et al. 2020

Proceedings of Singapore Healthcare

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“…Small bowel involvement of high-grade lymphoma is associated with perforation and increased mortality. 11 It is also important to remember that patients may present with GI bleeding because of GI lymphoma. Therefore, the role of endoscopic evaluation for PEL will be critical for the early diagnosis and management of this disease process.…”

Section: Discussionmentioning

confidence: 99%

Primary Effusion Lymphoma: Small Bowel Recurrence After Stem Cell Transplant

et al. 2021

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Primary effusion lymphoma (PEL) is a rare AIDS-associated non-Hodgkin lymphoma, growing in the serous body cavities as a lymphomatous effusion. The endoscopic features of PEL can mimic Kaposi sarcoma (KS). We present a case where PEL presented as small intestinal masses which had a similar macroscopic appearance to KS. Endoscopic evaluation was used with biopsies which confirmed the diagnosis of PEL. PEL is a differential of gastrointestinal KS. Accurate diagnosis is crucial for prognostication in these patients. Our case emphasizes that PEL presenting as intestinal tumors can mimic KS macroscopically. Although treatment for PEL and KS includes standard chemotherapy with concurrent antiretroviral therapy, early detection of PEL can improve overall survival in these patients.

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“…Las razones para la perforación en pacientes que reciben quimioterapia son la rápida necrosis del tumor, lisis tumoral y alteraciones del tejido por la rápida granulación. La tasa de perforación en linfomas de células T es mayor (41 -50 %) que en células B (30 %), por su afectación de la mucosa con invasión de paredes vasculares llevando a isquemia y necrosis 18,19 .…”

Section: Perforación Intestinalunclassified

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

Molina-Valencia

Delgado-López

2021

Rev Colomb Cir

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Introducción. El linfoma puede afectar el tracto gastrointestinal de manera primaria o secundaria, y representa hasta el 2 % de todas las neoplasias malignas del intestino delgado y colon. El tracto gastrointestinal es la ubicación extraganglionar primaria más común en el linfoma no Hodgkin. Métodos. Se realizó una búsqueda de la literatura en las principales bases de datos académicas, con revisión de textos publicados sobre el tema en los últimos 5 años. Discusión. La presentación clínica del linfoma con compromiso gastrointestinal es inespecífica y, hasta en la mitad de los pacientes, se puede presentar de manera inicial con complicaciones que requieran manejo quirúrgico. Entre las principales se encuentran la perforación intestinal, el sangrado digestivo y la obstrucción intestinal.

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Do total parenteral nutrition and bowel rest reduce the risk for perforation in patients with gastrointestinal tract lymphoma receiving chemotherapy?

Cited by 7 publications

References 12 publications

Adult malnutrition, nutritional interventions and outcomes in Singapore: a scoping review of local studies for the past 20 years

Adult malnutrition, nutritional interventions and outcomes in Singapore: a scoping review of local studies for the past 20 years

Primary Effusion Lymphoma: Small Bowel Recurrence After Stem Cell Transplant

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

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