Do the filarial lymphoedema patients’‘3 months recall’ on acute dermato‐lymphangio‐adenitis (ADLA) correlate with streptococcal serology?

Britto, Lourduraj John De; Das, Lalit Kumar

doi:10.1111/j.1468-3083.2011.04182.x

Cited by 2 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Individuals presenting with filarial lymphedema with or without wounds and had resided in the community for the past ten (10)…”

Section: Study Participantsmentioning

confidence: 99%

“…Moreover, bacteriological study on the skin biopsy, lymph node, lymph showed populations of Staphylococcus epidermis , S. hominis , Micrococcus species and luteus , Corynebacterium , Streptococcus acidominus which hitherto are sterile sites 8 . More specifically, there has been a report of direct link between the group A streptococci infection with acute dermatolymphangioadenitis (ADLA) as a higher tire of anti‐streptolysin O (ASO) was observed to positively correlate with ADLA experience by LF patients 10 . This observation has been suggested to be due to the Gram‐positive bacteria (group A streptococci) invading the skin barrier into the peripheral blood 11,12 …”

Section: Introductionmentioning

confidence: 99%

“…8 More specifically, there has been a report of direct link between the group A streptococci infection with acute dermatolymphangioadenitis (ADLA) as a higher tire of antistreptolysin O (ASO) was observed to positively correlate with ADLA experience by LF patients. 10 This observation has been suggested to be due to the Gram-positive bacteria (group A streptococci) invading the skin barrier into the peripheral blood. 11,12 LF is documented to infect nearly 120 million individuals worldwide with almost 40 million individuals currently suffering from varying degrees of disability and morbidity.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Bacterial diversity significantly reduces toward the late stages among filarial lymphedema patients in the Ahanta West District of Ghana: A cross‐sectional study

Asiedu

Kini

Aglomasa

et al. 2022

Health Science Reports

View full text Add to dashboard Cite

Background: Lymphatic Filariasis (LF), a neglected tropical disease, has been speculated to be complicated by secondary bacteria, yet a systematic documentation of these bacterial populations is lacking. Thus, the primary focus of this study was to profile bacteria diversity in the progression of filarial lymphedema among LF individuals with or without wounds.Methods: A cross-sectional study design recruited 132 LF individuals presenting with lymphedema with or without wounds from eight communities in the Ahanta West District in the Western Region, Ghana. Swabs from the lymphedematous limbs, ulcers, pus, and cutaneous surfaces were cultured using standard culture-based techniques. The culture isolates were subsequently profiled using Matrix-assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.Results: Of the 132 LF participants recruited, 65% (85) had filarial lymphedema with no wounds. In total, 84% (235) of the bacterial isolates were identified. The remaining 16% (46) could not be identified with the method employed. Additionally, 129(55%) of the strains belonged to the phylum Firmicutes, while 61 (26%) and 45 (19%) represented Proteobacteria and Actinobacteria, respectively. Generally, irrespective of the samples type (i.e., wound sample and non-wound samples), there was a sharp increase of bacteria diversity from Stages 1 to 3 and a drastic decrease in these numbers by Stage 4, followed by another surge and a gradual decline in the advanced stages of the disease. The Shannon Diversity Index and Equitability for participants with and without wounds were (3.482, 0.94) and (3.023, 0.75), respectively. Further, Staphylococcus haemolyticus and Escherichia coli showed resistance to tetracycline, chloramphenicol, and penicillin.

show abstract

“…Individuals presenting with filarial lymphedema with or without wounds and had resided in the community for the past ten (10)…”

Section: Study Participantsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%