Do persistent organic pollutants stimulate cyanobacterial blooms?

Harris, Theodore D.; Smith, Val H.

doi:10.5268/iw-6.2.887

Cited by 50 publications

(28 citation statements)

References 51 publications

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“…), with some taxa being naturally tolerant to the herbicide (eg several strains of cyanobacteria; Forlani et al . ; Harris and Smith ). Moreover, irrespective of whether a given species is capable of using glyphosate as a P source, bioavailable P compounds released via biodegradation can be assimilated by other organisms, stimulating their proliferation, as has been observed in cyanobacterial communities in Lake Erie (Saxton et al .…”

Section: Glyphosate and Phosphorus: Accumulation Transport And Bioamentioning

confidence: 96%

The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds

Hébert

Fugère

Gonzalez

2018

Frontiers in Ecol & Environ

120

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Glyphosate is the most extensively used pesticide worldwide. In addition to raising ecotoxicological concerns, the use of glyphosate adds phosphorus (P) to agricultural landscapes, influencing the accumulation and cycling of P in soil and nearby surface waters. Yet pesticides have been largely ignored when monitoring anthropogenic sources of P in agricultural watersheds. Estimating the supply of P derived from glyphosate use, both globally and in the US alone, we show that trends have markedly increased over the past two decades. Across the US, mean inputs of glyphosate‐derived P increased from 1.6 kg P km−2 in 1993 to 9.4 kg P km−2 in 2014, with values frequently exceeding 20 kg P km−2 in areas planted with glyphosate‐resistant crops. Although still a minor source of P relative to fertilizers, P inputs from glyphosate use have now reached levels comparable to those from sources for which P regulations were initiated in the past. We thus argue for greater recognition of glyphosate's influence on P flow in watershed research and management.

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Section: Glyphosate and Phosphorus: Accumulation Transport And Bioamentioning

confidence: 96%

The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds

Hébert

Fugère

Gonzalez

2018

Frontiers in Ecol & Environ

120

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“…nutrient cycling, water quality and HAB regulation) could be significant (Woolhouse & Ward 2013; Watts et al 2017). Research on the impacts of chemicals on HAB regulation has been extremely limited to date and has generally focused on the effects of pesticides on HABs in freshwater systems (Relyea 2009;Beketov et al 2013;Harris & Smith 2015;Staley et al 2015).…”

Section: Disease and Use Of Chemical Treatments To Control Pathogens mentioning

confidence: 99%

Assessing risks and mitigating impacts of harmful algal blooms on mariculture and marine fisheries

Brown

Lilley

Shutler

et al. 2019

Reviews in Aquaculture

133

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Aquaculture is the fastest growing food sector globally and protein provisioning from aquaculture now exceeds that from wild capture fisheries. There is clear potential for the further expansion of marine aquaculture (mariculture), but there are associated risks. Some naturally occurring algae can proliferate under certain environmental conditions, causing deoxygenation of seawater, or releasing toxic compounds (phycotoxins), which can harm wild and cultured finfish and shellfish, and also human consumers. The impacts of these so-called harmful algal blooms (HABs) amount to approximately 8 $billion/yr globally, due to mass mortalities in finfish, harvesting bans preventing the sale of shellfish that have accumulated unsafe levels of HAB phycotoxins and unavoided human health costs. Here, we provide a critical review and analysis of HAB impacts on mariculture (and wild capture fisheries) and recommend research to identify ways to minimise their impacts to the industry. We examine causal factors for HAB development in inshore versus offshore locations and consider how mariculture itself, in its various forms, may exacerbate or mitigate HAB risk. From a management perspective, there is considerable scope for strategic siting of offshore mariculture and holistic Environmental Approaches for Aquaculture, such as offsetting nutrient outputs from finfish farming, via the co-location of extractive shellfish and macroalgae. Such pre-emptive, ecosystem-based approaches are preferable to reactive physical, chemical or microbiological control measures aiming to remove or neutralise HABs and their phycotxins. To facilitate mariculture expansion and long-term sustainability, it is also essential to evaluate HAB risk in conjunction with climate change.

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“…Visible accumulations of cyanobacterial biomass in the form of surface blooms have been increasing over the past few decades [1,2], mainly due to eutrophication associated with increased nutrient loading to surface waters [3,4]. In addition, other factors including global warming, changes in hydrology, and pesticide use may be acting synergistically to accelerate cyanobacterial blooms [1,[5][6][7][8]. These blooms can also be harmful since cyanobacteria have the potential to produce a range of toxins, including hepatotoxins, neurotoxins, and endotoxins [9,10].…”

Section: Introductionmentioning

confidence: 99%

Metabolome Variation between Strains of Microcystis aeruginosa by Untargeted Mass Spectrometry

Racine

Saleem

Pick

2019

Toxins

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Cyanobacteria are notorious for their potential to produce hepatotoxic microcystins (MCs), but other bioactive compounds synthesized in the cells could be as toxic, and thus present interest for characterization. Ultra performance liquid chromatography and high-resolution accurate mass spectrometry (UPLC-QTOF-MS/MS) combined with untargeted analysis was used to compare the metabolomes of five different strains of the common bloom-forming cyanobacterium, Microcystis aeruginosa. Even in microcystin-producing strains, other classes of oligopeptides including cyanopeptolins, aeruginosins, and aerucyclamides, were often the more dominant compounds. The distinct and large variation between strains of the same widespread species highlights the need to characterize the metabolome of a larger number of cyanobacteria, especially as several metabolites other than microcystins can affect ecological and human health.Key Contribution: Metabolome variation between M. aeruginosa strains, highlighted by oligopeptide detection and identification, using a new, untargeted analytical workflow.Toxins 2019, 11, 723 2 of 18 and Planktothrix [17,18], MCs cause the inhibition of protein phosphatases 2A and 1 in vertebrates, which leads to an accumulation of phosphorylated proteins in cells. This accumulation can affect different metabolic pathways, including the inhibition of tumor suppressor proteins, cell proliferation and eventually, death [9,[19][20][21]. Despite many ecological impacts, the biological role of MCs within cyanobacteria remains unknown, which makes their control difficult. Remarkably, the cell concentrations of MCs in toxigenic taxa can reach those of chlorophyll a [22], the primary pigment involved in photosynthesis in cyanobacteria, algae and higher plants.Thus far over 269 variants have been identified with molecular weights varying between 880 and 1200 Da [10,23]. Amino acid variation in various positions of the cyclic molecule affects the degree of toxicity in vertebrates, as shown by LD 50 values between 50 µg/kg (MC-LA) and 800 µg/kg (MC-RR) in mice after intraperitoneal injection [16]. Microcystins are thus potentially more lethal to vertebrates than several highly potent poisons, such as sarin [24]. Increasing toxic effects are observed when hydrophobic amino acids (e.g., methylated amino acids) are present in the molecule, which can facilitate MC penetration into the tissues [25]. However, the ADDA moiety of the molecule (3-amino-9-methoxy-10-phenyl-2,6,8-trimethyldeca-4,6-dienoic acid), found in all MC variants, is known to have a major role in the toxicity [25].In addition to microcystins, cyanobacteria can produce a wide range of bioactive compounds. These include an extraordinary diversity of oligopeptides (e.g., cyanopeptolins, aeruginosins, microviridins) [26]. Several may also be bioactive or even toxic to vertebrates since many are produced through the same metabolic pathway as the MCs [27] and have similar structures [28]. Besides the public and environmental health needs for more research on these co...

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Do persistent organic pollutants stimulate cyanobacterial blooms?

Cited by 50 publications

References 51 publications

The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds

The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds

Assessing risks and mitigating impacts of harmful algal blooms on mariculture and marine fisheries

Metabolome Variation between Strains of Microcystis aeruginosa by Untargeted Mass Spectrometry

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