Do Pain Qualities and Spatial Characteristics Make Independent Contributions to Interference With Physical and Emotional Functioning?

Jensen, Mark P.; Dworkin, Robert H.; Gammaitoni, Arnold R.; Olaleye, David O.; Oleka, Napoleon; Galer, Bradley S.

doi:10.1016/j.jpain.2006.02.012

Cited by 38 publications

(36 citation statements)

References 25 publications

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“…6,15,18,21,23,24,44 Analyses of changes with lidocaine patch 5% treatment in several of these studies for NPS items and scales and of the relationships between NPS items and physical and emotional functioning have been reported previously. 2,19,22,26,27 All participants provided informed consent before any study procedures were initiated. The protocols conformed to the 1975 Declaration of Helsinki and were approved by the following institutional review boards: To participate in the trials, patients had to have an average daily pain intensity that was either Ͼ4 or Ն4 (depending on the trial) on a 0-10 numerical rating scale and remain on a stable analgesic regimen for at least 1 week before study entry.…”

Section: Study Participants and Proceduresmentioning

confidence: 99%

Symptom Profiles Differ in Patients With Neuropathic Versus Non-neuropathic Pain

Dworkin

Jensen

Gammaitoni

et al. 2007

The Journal of Pain

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114

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Section: Study Participants and Proceduresmentioning

confidence: 99%

Symptom Profiles Differ in Patients With Neuropathic Versus Non-neuropathic Pain

Dworkin

Jensen

Gammaitoni

et al. 2007

The Journal of Pain

Self Cite

114

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“…In a small study (n=97), comparing pain quality descriptors associated with RA, localized OA, and generalized OA, those with generalized OA were more varied in their selection of descriptors [54]. In another pain quality study using pretreatment data from clinical trials of topical lidocaine for chronic pain, the authors proposed that because OA pain was more diffuse, it could be more difficult to describe, while focal pain might be more discriminative of pain quality measures [27,28]. These reports are consistent with our finding that older adults who endorsed descriptors in all 3 categories had a higher prevalence of multi-site and widespread pain.…”

Section: Discussionmentioning

confidence: 99%

Pain quality descriptors in community-dwelling older adults with nonmalignant pain

Thakral

Shi

Foust

et al. 2016

PAIN

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This study aimed to characterize the prevalence of various pain qualities in older adults with chronic non-malignant pain and determine the association of pain quality to other pain characteristics namely: severity, interference distribution, and pain-associated conditions. In the population-based MOBILIZE Boston Study, 560 participants aged≥70 years reported chronic pain in the baseline assessment, which included a home interview and clinic exam. Pain quality was assessed using a modified version of the McGill Pain Questionnaire (MPQ) consisting of 20 descriptors, from which 3 categories were derived: cognitive/affective, sensory and neuropathic. Presence of ≥2 pain-associated conditions was significantly associated with 18 of the 20 pain quality descriptors. Sensory descriptors were endorsed by nearly all older adults with chronic pain (93%), followed by cognitive/affective (83.4%) and neuropathic descriptors (68.6%). Neuropathic descriptors were associated with the greatest number of pain-associated conditions including osteoarthritis of the hand and knee. More than half of participants (59%) endorsed descriptors in all 3 categories and had more severe pain and interference, and multi-site or widespread pain than those endorsing 1 or 2 categories. Strong associations were observed between pain quality and measures of pain severity, interference, and distribution (p<.0001). Findings from this study indicate that older adults have multiple pain-associated conditions which likely reflect multiple physiological mechanisms for pain. Linking pain qualities with other associated pain characteristics serves to develop a multidimensional approach to geriatric pain assessment. Future research is needed to investigate the physiological mechanisms responsible for the variability in pain qualities endorsed by older adults.

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“…Chronic pain persists beyond three months and is characterized by repeated or continuous pain episodes [6]. Other pain dimensions are quantitative (intensity) [7,8], qualitative (burning, pressing pain) [9], and spatial measures (whether the pain is local, regional or widespread) [10-12]. Chronic widespread pain (CWP) is an important measure of the global burden of pain [1,13], with a reported prevalence of 4% to 18% [14,15].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and long-term predictors of persistent chronic widespread pain in the general population in an 11-year prospective study: the HUNT study

Mundal

Gråwe

Bjørngaard

et al. 2014

BMC Musculoskelet Disord

106

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BackgroundChronic widespread pain (CWP) is common and associated with prominent negative consequences. The aim of this study was to assess the prevalence of persistent CWP in an 11-year prospective cohort study in the general population, and to examine anxiety, depression, alcohol use, poor sleep, body mass index (BMI) and chronic disease, along with demographic, lifestyle and other health-related variables as possible predictors for the assumed CWP persistence.MethodsCWP was defined as having pain at three or more predefined sites (involving the trunk and upper and lower limbs) for at least three months in the last year. We used a Norwegian general population cohort of 28,367 individuals who responded to both the second (1995–1997) and the third (2006–2008) waves of the Nord-Trøndelag Health Study (HUNT2 and HUNT3, respectively). Data were analysed with logistic regression models.ResultsCWP prevalence in HUNT2 was 17%. Of those reporting CWP in HUNT2, 53% still reported CWP at follow-up in HUNT3. Adjusted analyses revealed that depression and alcohol consumption were not substantially associated with the 11-year prospective CWP outcome. Poor sleep, obesity and chronic disease predicted persistent CWP, and being male and/or 60 years or older was protective.ConclusionsThis cohort study revealed that nearly half of the participants with baseline CWP resolved from CWP 11 years later. Among those whose CWP did not resolve, obesity, sleeping problems and chronic disease predicted CWP persistence, while aging and male sex was protective. Anxiety, mixed anxiety and depression, former smoking, and overweight were weakly associated, while depression, moderate exercise, and alcohol use were not associated with persistent CWP.

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Do Pain Qualities and Spatial Characteristics Make Independent Contributions to Interference With Physical and Emotional Functioning?

Cited by 38 publications

References 25 publications

Symptom Profiles Differ in Patients With Neuropathic Versus Non-neuropathic Pain

Symptom Profiles Differ in Patients With Neuropathic Versus Non-neuropathic Pain

Pain quality descriptors in community-dwelling older adults with nonmalignant pain

Prevalence and long-term predictors of persistent chronic widespread pain in the general population in an 11-year prospective study: the HUNT study

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