“…Two studies from the 1990s each found that MOs occurred at roughly one-half of all early childhood health care encounters. 6,12 Two additional studies from the same era found that 50%-75% of children experienced at least one MO by the time they were 24 months old. 13,14 Although the frequencies of MOs reported in the earlier studies are in the same range as our own, the previously reported frequencies are slightly lower likely in part because those studies examined only 3 or 4 vaccine series (vs the 7 in our study) and had relatively low thresholds for valid medical contraindication to vaccination (eg, low-grade fever, history of fever in the last week, mild respiratory illness, sinusitis, and the need for follow up within 48 hours) reflecting the recommendations of the time.…”