Do high soil geochemical backgrounds of selenium and associated heavy metals affect human hepatic and renal health? Evidence from Enshi County, China

Li, Minglong; Yang, Boyong; Ju, Zhaoqing; Liang, Qing Quan; Xu, Keyuan; Wang, Minghua; Chen, Can; Zhang, Kai; Zhang, Zixiong; Xiang, Sufang; Zheng, Jie; Yang, B.; Huang, Chuying; Zheng, Deshun

doi:10.1016/j.scitotenv.2023.163717

Cited by 3 publications

(5 citation statements)

References 56 publications

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“…The median U‐Cd concentrations of residents who relied on local rice and ecdemic rice within the last 1–2 years as their main food in the study area of Zhuxi were 7.050 μg/L and 7.240 μg/L, respectively, which were much higher than the B‐Cd levels of the general population in China. For example, the median U‐Cd concentrations of healthy individuals without occupational exposure to Cd in Lichuan County, Hubei Province, Hunan Province, and Xinxiang area, Henan Province, were 2.243 μg/L ( n = 91), 2.180 μg/L ( n = 1,168), and 2.260 μg/L ( n = 651), respectively (Li, Yang, et al., 2023 ; Wang et al., 2015 ). Consistent with B‐Cd, although some residents in the exposed black shale areas in Zhuxi County stopped consuming local rice within the last 1–2 years, the U‐Cd content did not significantly decrease ( P = 0.858), indicating that they experienced long‐term internal exposure to Cd.…”

Section: Resultsmentioning

confidence: 99%

“…In the study area of Zhuxi County, 10 Cambrian black shale samples and 56 arable land surface soil samples (0–20 cm) were collected. Rice is the staple food of residents in southern China, and the Cd content in rice may be important for the daily total intake of residents in the area (Khanam et al., 2020 ; Li, Yang, et al., 2023 ; Mao et al., 2019 ). Ninety rice samples were collected in the Enshi study area, and 78 rice samples (41 local rice and 37 ecdemic rice) were collected in the Zhuxi study area.…”

Section: Methodsmentioning

confidence: 99%

“…The natural high‐Se areas in China are mostly related to the exposure and weathering of black shale in the middle Permian and low Cambrian. For example, Middle Permian black shale is exposed in Enshi County, Hubei Province (Li et al., 2020 , 2022 ), while Lower Cambrian black shale is exposed in Ziyang County, Shaanxi Province (Jie & Luo, 2017 ), Longyou County, Zhejiang Province (Li, Yang, et al., 2023 ), and the Changde area, Hunan Province (Ni et al., 2016 ). However, black shale in China is also highly enriched in Cd, resulting in high Cd contents in soil, water, and crops in these high‐Se areas (Li, Yang, et al., 2023 ).…”

Section: Introductionmentioning

confidence: 99%

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Effects of Selenium and Cadmium on Human Liver and Kidney Functions in Exposed Black Shale Areas

Li,

Qiu,

et al. 2024

GeoHealth

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Animal experiments suggest that selenium (Se) may alleviate cadmium (Cd) toxicity in animal liver and kidneys, but its effect on human liver and kidneys remains uncertain. In China, areas with black shale have shown elevated levels of Se and Cd. According to the USEPA (U.S. Environmental Protection Agency) evaluation method, the soil and rice in these areas pose significant risks. In black shale regions such as Enshi and Zhuxi County, residents who long‐term consume local rice may surpass safe Se and Cd intake levels. Significantly high median blood Se (B‐Se) and urine selenium (U‐Se) levels were detected in these areas, measuring 416.977 μg/L and 352.690 μg/L and 104.527 μg/L and 51.820 μg/L, respectively. Additionally, the median blood Cd (B‐Cd) and urine Cd (U‐Cd) levels were markedly elevated at 4.821 μg/L and 3.848 μg/L and at 7.750 μg/L and 7.050 μg/L, respectively, indicating substantial Cd exposure. Nevertheless, sensitive liver and kidney biomarkers in these groups fall within healthy reference ranges, suggesting a potential antagonistic effect of Se on Cd in the human body. Therefore, the USEPA method may not accurately assess Cd risk in exposed black shale areas. However, within the healthy ranges, residents in the Enshi study area had significantly greater median levels of serum creatinine and cystatin C, measuring 67.3 μmol/L and 0.92 mg/L, respectively, than those in Zhuxi did (53.6 μmol/L and 0.86 mg/L). In cases of excessive Se and Cd exposure, high Se and Cd levels impact the filtration function of the human kidney to some extent.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of Selenium and Cadmium on Human Liver and Kidney Functions in Exposed Black Shale Areas

Li,

Qiu,

et al. 2024

GeoHealth

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“…The soil specimen underwent a process of natural desiccation, pulverization, and filtration through a 10-mesh nylon sieve before being dispatched to the laboratory for meticulous analysis and evaluation. The procedures for soil sampling and processing adhered rigorously to the specifications outlined in DZ/T 0295-2016 [24,25]. At designated sampling nodes, with the GPS positioning point serving as the focal point, 3-5 sampling nodes are delineated within a radius of 20-50 m in all directions.…”

Section: Sample Acquisitionmentioning

confidence: 99%

Section: Sample Acquisitionmentioning

confidence: 99%

Characteristics of Soil Heavy Metal Pollution and Health Risks in Chenzhou City

Kuang,

Chen,

Zhu

2024

Processes

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The objective of this inquiry is to illuminate the attributes of heavy metal contamination and evaluate the potential ecological hazards inherent in the surface soil of Chenzhou City. A comprehensive analysis was conducted on 600 systematically collected soil samples within the study area, utilizing enrichment factors, geo-accumulation indices, comprehensive pollution indices, potential ecological hazard indices, and health risk assessment models to evaluate the degree of heavy metal contamination in the soil, potential ecological risks, and associated health hazards. The findings reveal that the average enrichment factor (EF) for each heavy metal is below 2, with the hierarchy from highest to lowest being Hg > Cd > Cu > Pb > Ni > Zn > Cr > As. Approximately 78.67% of soil samples exhibit no pollution to weak pollution levels based on heavy metal enrichment factors. Moreover, the comprehensive pollution index (IPIN) indicates that 95.17% of soil samples are within safe and pollution-free levels, indicating an overall environmentally secure setting. However, 2.67% of samples display heightened potential ecological risk levels, primarily concentrated in the southwestern region of the study area, influenced by nearby industrial activities. Additionally, it is noteworthy that both the non-carcinogenic and carcinogenic health hazards emanating from soil heavy metals to adult individuals lie within tolerable thresholds. Among these, arsenic (As), chromium (Cr), and lead (Pb) have been discerned as the principal non-carcinogenic agents. It is of particular significance that only a solitary soil specimen, located in the southwestern quadrant of the investigative region, manifests detectable health perils for children.

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Rhizosphere Enrichment and Crop Utilization of Selenium and Metals in Typical Permian Soils of Enshi

Jiang,

Zhou,

et al. 2024

Chemosphere

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Do high soil geochemical backgrounds of selenium and associated heavy metals affect human hepatic and renal health? Evidence from Enshi County, China

Cited by 3 publications

References 56 publications

Effects of Selenium and Cadmium on Human Liver and Kidney Functions in Exposed Black Shale Areas

Effects of Selenium and Cadmium on Human Liver and Kidney Functions in Exposed Black Shale Areas

Characteristics of Soil Heavy Metal Pollution and Health Risks in Chenzhou City

Rhizosphere Enrichment and Crop Utilization of Selenium and Metals in Typical Permian Soils of Enshi

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