Do females behave differently in COPD exacerbation?

Kılıç, Hatice; Köktürk, Nurdan; Sarı, Gülçin; Çakır, Mustafa

doi:10.2147/copd.s78952

Cited by 36 publications

(32 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This finding concurred with previous results, showing females had lower 30-day all-cause readmissions 43 and fewer ICU admissions due to COPD exacerbation in the previous year. 21 Males, based on review and retrospective study, in accordance with our estimates, had a higher frequency of readmission. 44,45 Because females were less likely to self-report COPD and have COPD as a primary diagnosis, when women were readmitted within 30 days their reasons for readmission may not have been caused by COPD.…”

Section: Discussionsupporting

confidence: 90%

“…7,11,19 Males were more likely to be readmitted, 19,20 whereas females had fewer comorbidities and might be undertreated for COPD, itself. 21 Although gender plays an important role in COPD readmission, few studies have navigated how gender might affect the COPD-related 30-day readmission rate among patients with and without additional comorbidities. We hypothesized that both male and female COPD patients with comorbidities were more likely to be readmitted, compared to male patients without comorbidities.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk</p>

Lin

Xue

Deng

et al. 2020

COPD

View full text Add to dashboard Cite

Background and Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. COPD is expensive to treat, whereas the quality of care is difficult to evaluate due to the high prevalence of multi-morbidity among COPD patients. In the US, the Hospital Readmissions Reduction Program (HRRP) was initiated by the Centers for Medicare and Medicaid Services to penalize hospitals for excessive 30-day readmission rates for six diseases, including COPD. This study examines the difference in 30-day readmission risk between COPD patients with and without comorbidities. Methods: In this retrospective cohort study, we used Cox regression to estimate the hazard ratio of 30-day readmission rates for COPD patients who had no comorbidity and those who had one, two or three, or four or more comorbidities. We controlled for individual, hospital and geographic factors. Data came from three sources: Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases (SID), Area Health Resources Files (AHRF) and the American Hospital Association's (AHA's) annual survey database for the year of 2013. Results: COPD patients with comorbidities were less likely to be readmitted within 30 days relative to patients without comorbidities (aHR from 0.84 to 0.87, p < 0.05). In a stratified analysis, female patients with one comorbidity had a lower risk of 30-day readmission compared to female patients without comorbidity (aHR = 0.80, p < 0.05). Patients with public insurance who had comorbidities were less likely to be readmitted within 30 days in comparison with those who had no comorbidity (aHR from 0.79 to 0.84, p < 0.05). Conclusion: COPD patients with comorbidities had a lower risk of 30-day readmission compared with patients without comorbidity. Future research could use a different study design to identify the effectiveness of the HRRP.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

<p>Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk</p>

Lin

Xue

Deng

et al. 2020

COPD

View full text Add to dashboard Cite

show abstract

“…The present study, as in the study by Kilic et al,20 showed that women experienced significantly more exacerbations. However, the increase of exacerbations in relation to higher age, found in other studies,7,9 was not found in this sample.…”

Section: Discussionsupporting

confidence: 87%

“…With regard to disease characteristics, more men than women were diagnosed with comorbidities, except for osteoporosis and depression/anxiety, which occurred more frequently in women, which was also reported by Aryal et al4 Differences in comorbidity profile were also found by Kilic et al,20 who reported that women, to a larger extent, had sleep disorder, chronic kidney disease, anemia, and gastroesophageal reflux disease 20. The present study, as in the study by Kilic et al,20 showed that women experienced significantly more exacerbations.…”

Section: Discussionsupporting

confidence: 63%

Management of COPD, equal treatment across age, gender, and social situation? A register study

Henoch

Strang

Ekberg-Jansson

2016

COPD

View full text Add to dashboard Cite

Chronic obstructive pulmonary disease (COPD) is a progressive chronic disease where treatment decisions should be based on disease severity and also should be equally distributed across age, gender, and social situation. The aim of this study was to determine to what extent patients with COPD are offered evidence-based interventions and how the interventions are distributed across demographic and clinical factors in the sample. Baseline registrations of demographic, disease-related, and management-related variables of 7,810 patients in the Swedish National Airway Register are presented. One-third of the patients were current smokers. Patient-reported dyspnea and health-related quality of life were more deteriorated in elderly patients and patients living alone. Only 34% of currently smoking patients participated in the smoking cessation programs, and 22% of all patients were enrolled in any patient education program, with women taking part in them more than men. Less than 20% of the patients had any contact with physiotherapists or dieticians, with women having more contact than men. Men had more comorbidities than women, except for depression and osteoporosis. Women were more often given pharmacological treatments. With increasing severity of dyspnea, participation in patient education programs was more common. Dietician contact was more common in those with lower body mass index and more severe COPD stage. Both dietician contact and physiotherapist contact increased with deteriorated health-related quality of life, dyspnea, and increased exacerbation frequency. The present study showed that COPD management is mostly equally distributed across demographic characteristics. Only a minority of the patients in the present study had interdisciplinary team contacts. Thus, this data shows that the practical implementation of structured guidelines for treatment of COPD varies, to some extent, with regard to age and gender. Also, disease characteristics influence guideline implementation for each individual patient. Quality registers have the strength to follow-up on compliance with guidelines and show whether an intervention needs to be adapted prior to implementation in health care practice.

show abstract

“…As in other studies, the male sex was a risk factor of exacerbation due to the smoking habits. However, other studies have reported a higher risk of exacerbation in females [ 30 ].…”

Section: Discussionmentioning

confidence: 97%

Risk of exacerbation in chronic obstructive pulmonary disease: a primary care retrospective cohort study

et al. 2015

View full text Add to dashboard Cite

BackgroundThe risk of exacerbation in chronic obstructive pulmonary disease (COPD) depends on the severity of disease and other less well known factors. Predictive models of exacerbation are more accurate than the forced expiratory volume in one second (FEV1). The objective was to design a model that predicts the risk of exacerbation in COPD.MethodsRetrospective cohort study with data from the electronic medical records of patients diagnosed with COPD in the province of Lleida (Spain). A total of 2501 patients were followed during 3 years. The dependent variable was acute exacerbation; independent variables were: clinical parameters, spirometry results, severity of disease, influenza and 23-valent pneumococcal immunisation, comorbidities, smoking and history of exacerbation. The association of these variables with disease exacerbation was measured by the adjusted odds ratio using a logistic regression model.ResultsMean age at the start of the study was 68.38 years (SD = 11.60) and 74.97 % patients were men; severity of disease was considered mild in 50.82 % of patients, moderate in 35.31 %, severe in 9.44 % and very severe in 4.44 %. During the three year study period up to 83.17 % of patients experienced at least one exacerbation. Predictive factors in the model were age, gender, previous exacerbations, influenza and 23-valent pneumococcal immunisations, number of previous visits to the General Practice and severity (GOLD), with an area under the ROC curve (AUROC) of 0.70.ConclusionsThis model can identify patients at high risk of acute exacerbation. Preventive measures and modification of treatment in these high-risk patients would improve survival.

show abstract

Do females behave differently in COPD exacerbation?

Cited by 36 publications

References 35 publications

<p>Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk</p>

<p>Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk</p>

Management of COPD, equal treatment across age, gender, and social situation? A register study

Risk of exacerbation in chronic obstructive pulmonary disease: a primary care retrospective cohort study

Contact Info

Product

Resources

About