Do Elastic Abdominal Binders Reduce Postoperative Pain and Blood Loss?

Abstract

modulators. DNA methytransferases (DNMT) appear to regulate gene activity during decidualization, but relative expression level by phase is not fully understood and has not been studied in abnormal uterine bleeding.METHODS: Immunohistochemistry was performed on tissue microarrays derived from 541 endometrial samples including secretory, proliferative, atrophic histopathologic diagnoses. Baseline demographic and clinical data were collected for all 541 study participants. The expression levels of DNMT1, DNMT3a, DNMT3b, estrogen receptor, and progesterone receptor were determined by staining scores, generated as the product of staining intensity and extent. Review was completed by a pathologist blinded to the clinical information. Statistical analysis of composite scores was performed using JMP 9.0. RESULTS:For each phase of the menstrual cycle, epithelial and stromal cell nuclei immunostained for DNMT1, DNMT3a, and DNMT3b. Although tissue levels of DNMT3a and DNMT3b by staining score were lower in the midsecretory phases as compared with the proliferative phase, levels of DNMT1 were increased in the midsecretory phase. Overall expression of DNMT1 was higher in abnormal uterine bleeding, whereas DNMT3A and DNMT3b were unchanged.CONCLUSION: Our study is the largest yet to compare DNMT expression in human endometrium at different stages of decidualization and in abnormal uterine bleeding. Our study provides confirmatory evidence that DNMTs are expressed in human endometrium in a phase-specific manner. Further evaluation of a putative role for DNMTs in menstruation is warranted.

The Effects of Abdominal Binder on Wound Healing and Consumed Pain Medications After Cesarean Section: A Randomized Control Trial

“…A few studies have examined the effects of abdominal binders on CS complications (21,23,27). Some have addressed how abdominal binders impact wound healing (20,22,24) and pain medication consumption (21, 30) post-surgery.…”

“…However, the intervention group consumed significantly less pain medication than the control group at other intervals. In a number of similar studies on the effects of abdominal binders postlaparotomy and major abdominal procedures (Ali et (21) and between the first and fifth day post-major abdominal and laparotomy, using the SF-MPQ (Cheifetz et al, 2010) (18). Christoffersen (2014) demonstrated the ineffectiveness of using an abdominal binder post-surgery in umbilical and epigastric hernia repair; movement limitations, fatigue, quality of life, seroma formation, and pain remained unimproved (33).…”

“…Abdominal binders are a complementary therapy for major abdominal surgery, such as laparotomy, CS, cardiac surgery, etc. (20)(21)(22)(23)(24). Abdominal binders reduce pain by compressing the abdomen post-CS.…”

“…A study by Giller, in which the effect of abdominal binders post-CS was examined, indicated no effect on post-operative pain, perceived distress, hemoglobin, hematocrit, and extent of painkiller consumption (27). Gustafson used such a binder to relieve pain the first day post-surgery; hemoglobin and hematocrit levels were unaffected (21).…”

The benefit of elastic abdominal binders after cesarean section in rural area: A Randomized Controlled Pilot Trial

“…Several studies has shown that use of an elastic abdominal binder reduces postoperative pain and distress. 7,13,14 Postoperative pain also influenced breastfeeding and infant care. 15 Our study showed the decrease of pain in abdominal binder; the benefit of elastic abdominal binders after cesarean section in rural area volume 22, issue 3, July -september 2023 *p-value was analyzed using non-parametric Mann-Whitney U test however, it was not different for SDS and BPI-SF in terms of pain's impact to daily life.…”