Abstract:Background Adalimumab induction and maintenance therapy have been applied to patients with Crohn's disease (CD). This study aimed to analyze the efficacy and safety of an optimized dose versus a standard dose of adalimumab in the treatment of CD.Methods It was a retrospective study involving 192 CD patients treated with adalimumab. According to the maintenance therapy following an induction therapy, CD patients were assigned to receive a standard dose (subcutaneously injected with 40mg of adalimumab every othe… Show more
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