“…Thus, late effects of conditioning regimens are of imminent clinical relevance in patients achieving a complete remission following ASCT. Secondary acute leukemias and other neoplastic diseases are still relevant clinical side effects after ASCT, and thus, treatment with total body irradiation (TBI) should be avoided . Conditioning regimens without total body irradiation and with less cardiopulmonary toxicities are of benefit in patients treated with ASCT.…”