Do blood growth factors offer additional benefit in refractory lateral epicondylitis? A prospective, randomized pilot trial of dry needling as a stand-alone procedure versus dry needling and autologous conditioned plasma

Stenhouse, Gregor; Sookur, Paul; Watson, Matt

doi:10.1007/s00256-013-1691-7

Cited by 80 publications

(68 citation statements)

References 25 publications

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“…However, a literature review reveals no work comparing the results of therapy using ACP preparations and those based on steroid preparations. Generally, literature focused on ACP application for LE is rather scare [20,21]. Our present findings demonstrate the efficiency of ACP therapy compared to betamethazone.…”

Section: Discussionsupporting

confidence: 65%

“…Similar findings were reported by Stenhouse et al, who compared ACP injections and ultrasound-guided dry needling. No significant difference between the two treatment groups was demonstrated at each follow-up interval [20]. Tetschke et al demonstrated beneficial effects of autologous proliferative therapies (ACP) and low-level laser application in the treatment of lateral epicondylitis at one year follow up.…”

Section: Discussionmentioning

confidence: 99%

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A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

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Purpose Chronic tendinopathy of lateral epicondyle of the humerus, commonly known as Btennis elbow^is one of the most frequent tendinopathies caused by recurrent overload of the muscle origins. The aim of the study was to assess the effectiveness of treating lateral epicondylitis (LE) with autologous conditioned plasma (ACP) and betamethasone injections, and to compare these methods over the course of a one year follow-up. Methods Patients were randomly placed into one of into two groups: 53 were treated with ACP, and 46 with 1 ml betamethasone injections and 2 ml of 1 % lignocaine. Both those groups were comparable in terms of initial DASH score. Results After six weeks and six months, the mean DASH score was significantly better in the betamethasone group, but was better in ACP group after one year. Full recovery (patients with no symptoms) at all time points was more common in the betamethasone group. A comparison of grouped DASH scores revealed more very good and good results in the ACP group after one year. More patients had pain symptoms related to injection in the ACP group than the betamethasone group. Conclusions ACP therapy of LE allows better results to be obtained at 12 months. Betamethasone injections give more rapid improvement, but the therapeutic effect is longer lasting in the ACP group.

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Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 99%

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

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“…Although dry needling itself may contribute to the tendon healing process, the addition of PRP has been shown to have a beneficial effect. 19 Our method of PRP preparation is quick, easy and reliable. It gives a platelet concentration of approximately two to three times serum.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound-guided platelet-rich plasma injection for distal biceps tendinopathy

et al. 2015

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Background: Distal biceps tendinopathy is an uncommon cause of elbow pain. The optimum treatment for cases refractory to conservative treatment is unclear. Platelet-rich plasma has been used successfully for other tendinopathies around the elbow. Methods: Six patients with clinical and radiological evidence of distal biceps tendinopathy underwent ultrasound-guided platelet-rich plasma (PRP) injection. Clinical examination findings, visual analogue score (VAS) for pain and Mayo Elbow Performance scores were recorded. Results: The Mayo Elbow Performance Score improved from 68.3 (range 65 to 85) (fair function) to 95 (range 85 to 100) (excellent function). The VAS at rest improved from a mean of 2.25 (range 2 to 5) pre-injection to 0. The VAS with movement improved from a mean of 7.25 (range 5 to 8) pre-injection to 1.3 (range 0 to 2). No complications were noted. Discussion: Ultrasound-guided PRP injection appears to be a safe and effective treatment for recalcitrant cases of distal biceps tendinopathy. Further investigation with a randomized controlled trial is needed to fully assess its efficacy.

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“…However, at 3 months follow up, there were no significant differences between the three groups using the patient-related tennis elbow evaluation (PRTEE). Stenhouse et al performed a randomized trial comparing 2 ml PRP injection with dry needling in 28 patients with refractory tennis elbow, with a mean duration of symptoms of 19 months [23]. The authors found that there was a trend towards greater clinical improvement, as measured by reduction in VAS scores, at 2 and 6 months for the PRP group compared to dry needling, but the differences were not significant.…”

Section: Platelet Rich Plasma (Prp)mentioning

confidence: 94%