Do adverse perinatal events predict mortality in schizophrenia during midlife?

Rautio, Nina; Jääskeläinen, Erika; Nordström, Tanja; Isohanni, Matti; Seppälä, Jussi

doi:10.1016/j.schres.2016.09.031

Cited by 2 publications

(1 citation statement)

References 42 publications

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“…To the authors' knowledge, the only studies with psychiatric follow-up of the offspring of antenatally depressed mothers until middle adulthood are from the general population-based Northern Finland 1966 Birth Cohort (NFBC 1966) [11,12,[22][23][24][25]. The adult male offspring of antenatally depressed mothers were found to have an increased risk for criminal behaviour, especially violent recidivism in the 33-year follow-up of the NFBC 1966, using the nationwide register of the Ministry of Justice on criminal offences [11].…”

Section: Introductionmentioning

confidence: 99%

Antisocial and borderline personality disorders in the offspring of antenatally depressed mothers – a follow-up until mid-adulthood in the Northern Finland 1966 birth cohort

Taka-Eilola

Veijola

Koskela

et al. 2019

Nordic Journal of Psychiatry

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is a medical doctor, specializing in psychiatry. She wrote her thesis on mental health in the adult offspring of antenatally depressed mothers. She is aiming to better understand the effects of antenatal depression on offspring, which could ultimately help prevent some of the childhood and later mental disorders. She is a board member of the Nordic branch of the International Marcé Society for Perinatal Mental Health, which is dedicated to supporting research and assistance surrounding prenatal & postpartum mental health for mothers, fathers, and their babies.

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Section: Introductionmentioning

confidence: 99%

Antisocial and borderline personality disorders in the offspring of antenatally depressed mothers – a follow-up until mid-adulthood in the Northern Finland 1966 birth cohort

Taka-Eilola

Veijola

Koskela

et al. 2019

Nordic Journal of Psychiatry

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The Role of Socioeconomic Position in the Association Between Mental Disorders and Mortality

Chen,

Ejlskov,

Laustsen

et al. 2024

JAMA Psychiatry

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ImportanceStudies are lacking summarizing how the association between mental disorders and mortality varies by socioeconomic position (SEP), particularly considering different aspects of SEP, specific types of mental disorders, and causes of death.ObjectiveTo investigate the role of SEP in the association between mental disorders and mortality and the association between SEP and mortality among people with mental disorders.Data SourcesMEDLINE, Embase, PsycINFO, and Web of Science were searched from January 1, 1980, through April 3, 2023, and a snowball search of reference and citation lists was conducted.Study SelectionInclusion criteria were observational studies estimating the associations between different types of mental disorders and mortality, stratified by SEP and between SEP and mortality in people with mental disorders.Data Extraction and SynthesisPairs of reviewers independently extracted data using a predefined data extraction form and assessed the risk of bias using the adapted Newcastle-Ottawa scale. Graphical analyses of the dose-response associations and random-effects meta-analyses were performed. Heterogeneity was explored through meta-regressions and sensitivity analyses.Main Outcomes and MeasuresAll-cause and cause-specific mortality.ResultsOf 28 274 articles screened, 71 including more than 4 million people with mental disorders met the inclusion criteria (most of which were conducted in high-income countries). The relative associations between mental disorders and mortality were similar across SEP levels. Among people with mental disorders, belonging to the highest rather than the lowest SEP group was associated with lower all-cause mortality (pooled relative risk [RR], 0.79; 95% CI, 0.73-0.86) and mortality from natural causes (RR, 0.73; 95% CI, 0.62-0.85) and higher mortality from external causes (RR, 1.18; 95% CI, 0.99-1.41). Heterogeneity was high (I2 = 83% to 99%). Results from subgroup, sensitivity, and meta-regression analyses were consistent with those from the main analyses. Evidence on absolute scales, specific diagnoses, and specific causes of death was scarce.Conclusion and RelevanceThis study did not find a sufficient body of evidence that SEP moderated the relative association between mental disorders and mortality, but the underlying mortality rates may differ by SEP group, despite having scarcely been reported. This information gap, together with our findings related to SEP and a possible differential risk between natural and external causes of death in individuals with specific types of mental disorders, warrants further research.

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Do adverse perinatal events predict mortality in schizophrenia during midlife?

Cited by 2 publications

References 42 publications

Antisocial and borderline personality disorders in the offspring of antenatally depressed mothers – a follow-up until mid-adulthood in the Northern Finland 1966 birth cohort

Antisocial and borderline personality disorders in the offspring of antenatally depressed mothers – a follow-up until mid-adulthood in the Northern Finland 1966 birth cohort

The Role of Socioeconomic Position in the Association Between Mental Disorders and Mortality

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