Do Adherence Rates and Glaucomatous Visual Field Progression Correlate?

Rossi, Gemma Caterina Maria; Pasinetti, Giulio Maria; Scudeller, Luigia; Radaelli, Rosella; Bianchi, Paolo Emilio

doi:10.5301/ejo.2010.6112

Cited by 130 publications

(112 citation statements)

References 30 publications

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“…Participants were more often female (63.7% versus 49.3%), χ 2 (2) = 4.44, p = .04, African-American (19.9% versus 6.0%), χ 2 (2) = 4.71, p = .03, and slightly younger ( M = 65.0 years versus 69.9), t (251) = 2.69, p = .008, than those who refused participation. There were no differences between participants and nonparticipants in the percentage of Latino/Latina patients or the percentage of patients with insurance ( ps > .65).…”

Section: Resultsmentioning

confidence: 99%

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Predictors of Adherence to Glaucoma Treatment in a Multisite Study

et al. 2014

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Background Poor adherence hinders glaucoma treatment. Studies have identified demographic and clinical predictors of adherence but fewer psychological variables. Purpose We examined predictors from four health behavior theories and past research. Methods In the baseline phase of a 3-site adherence study, before any intervention, 201 participants used electronic Medication Event Monitoring System (MEMS) bottles to monitor eyedrop use for 2 months, and completed questionnaires including self-reported adherence. Results MEMS showed 79% adherence and self-report 94% (0.5–1.5 missed weekly doses), but correlated only rs = .31. Self-efficacy, motivation, dose frequency, and non-minority race/ethnicity predicted 35% of variance in MEMS. Cues to action, self-efficacy, and intention predicted 20% of variance in self-reported adherence. Conclusions Self-efficacy, motivation, intention, cues to action, dose frequency, and race/ethnicity each independently predicted adherence. Other predictors from all theories were supported in bivariate analyses, but additional study is needed. Researchers and clinicians should consider psychological predictors of adherence.

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Section: Resultsmentioning

confidence: 99%

“…Eye drop medications are prescribed to preserve visual function and quality of life by reducing intraocular pressure (IOP), and regular eye drop use reduces the rate of glaucoma progression (2). However, nonadherence is an ongoing barrier to glaucoma treatment (3,4), with more than half of patients remaining nonadherent even after significant vision loss (5).…”

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Predictors of Adherence to Glaucoma Treatment in a Multisite Study

et al. 2014

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“…In a randomized clinical trial testing whether interventions can improve rates of adherence (as determined by an electronic dosing aid device), investigators found no significant difference in IOP between the intervention and observation groups, although adherence increased by 20%. 96 On the other hand, Rossi et al 97 retrospectively investigated the relationship between visual field progression and adherence rate in patients with glaucoma using an electronic dosing aid device. Seventy-one percent of patients with stable visual fields had a median adherence rate of 85%, whereas patients who progressed (29%) recorded a median adherence of 21%.…”

Section: Difficulties In Evaluating the Rate Of Progressionmentioning

confidence: 99%

Why Do People (Still) Go Blind from Glaucoma?

Susanna

Moraes

Cioffi

et al. 2015

Trans. Vis. Sci. Tech.

131

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“…What is known is that not all glaucoma patients adhere with their therapy all of the time, and there is growing evidence that this situation correlates with worse control of IOP, greater fluctuations in IOP and worsening of visual field defects [110][111][112][113]. Clinical studies have also shown that glaucoma patients who discontinue their medical therapy tend to do so within the first 6 months after initiation of treatment, indicating poor persistence with therapy [114,115].…”

Section: Adherence and Persistencementioning

confidence: 99%

Pharmacotherapy and Adherence Issues in Treating Elderly Patients with Glaucoma

Broadway

Cate

2015

Drugs Aging

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Glaucoma is a leading cause of visual morbidity throughout the world and is an age-related condition, the prevalence of which rises significantly with increasing age. Glaucoma, a condition affecting the optic nerve, has a variety of subtypes with multiple aetiological factors, the most important of which are intraocular pressure (IOP) and increasing age. Treatment by lowering of IOP is the only current method, for which there is evidence, by which the rate of progressive visual deterioration can be slowed or halted. Although there are surgical and laser treatments that are efficacious in lowering IOP, the most common manner in which patients with glaucoma control their IOP is with administration of daily topical ocular hypotensive drugs (eye drops). The variety of topical drugs utilised in the management of glaucoma all have the potential to have adverse effects and/or interactions with concomitant medications, many of which may be used for other age-related conditions. Adherence with appropriate medicines has a major effect on the outcome of medical conditions and this aspect applies to the management of glaucoma. There are certain specific issues that relate to the administration of topical agents, with respect to both adverse effects and adherence. Although many suspect poor adherence in elderly patients with glaucoma, relative to younger patients, adequate evidence for this is lacking. Furthermore, the manner by which adherence issues could be improved remains inadequately understood and poorly addressed. The aims of this article were to review, from a clinical perspective, the medical therapies currently used for glaucoma and discuss adherence issues with respect to the population of patients with glaucoma, who tend to be relatively elderly.

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Do Adherence Rates and Glaucomatous Visual Field Progression Correlate?

Cited by 130 publications

References 30 publications

Predictors of Adherence to Glaucoma Treatment in a Multisite Study

Predictors of Adherence to Glaucoma Treatment in a Multisite Study

Why Do People (Still) Go Blind from Glaucoma?

Pharmacotherapy and Adherence Issues in Treating Elderly Patients with Glaucoma

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