Do Additional Echocardiographic Variables Increase the Accuracy of E/e′ for Predicting Left Ventricular Filling Pressure in Normal Ejection Fraction? An Echocardiographic and Invasive Hemodynamic Study

Dokainish, Hisham; Nguyen, John; Sengupta, Ranjita; Pillai, Manu; Alam, Mahboob; Bobek, Jaromir; Lakkis, Nasser

doi:10.1016/j.echo.2009.11.015

Cited by 53 publications

(32 citation statements)

References 38 publications

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“…Most echocardiography laboratories are accustomed to measuring early diastolic DTI of the mitral annulus for the purpose of evaluating LV filling pressure [61] or using the mitral E/e 0 ratio to differentiate between pulmonary arterial and pulmonary venous hypertension [37,62]. Right-sided or tricuspid E/e 0 has been described as a method of evaluating RA pressure [63], and a recent study has confirmed its usefulness in the evaluation of RA pressure among individuals with PAH.…”

Section: Ra Pressurementioning

confidence: 97%

Obtaining accurate hemodynamics from echocardiography: achieving independence from right heart catheterization

Ristow

Schiller²

2010

Current Opinion in Cardiology

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Section: Ra Pressurementioning

confidence: 97%

Obtaining accurate hemodynamics from echocardiography: achieving independence from right heart catheterization

Ristow

Schiller²

2010

Current Opinion in Cardiology

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“…Thus, exercise is necessary to diagnose HFNEF in a significant proportion of patients with unexplained exertional dyspnea or fatigue and normal resting hemodynamics. Doppler echocardiography using the E/e' ratio is standardly used to identify noninvasively the elevation of LVFP under resting conditions 1,[11][12][13][14][15] . However, the ability of the E/e' ratio to determine exercise-induced LVFP elevation is unclear.…”

Section: Discussionmentioning

confidence: 99%

Variability of post-exercise pulmonary capillary wedge pressure recovery. Implications for noninvasive echocardiographic diagnostics

Meluzı́n

Hude²,

Krejčí³

et al. 2015

BIOMED PAP

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Aim. The aim of our study was to assess the course of immediate post-exercise pulmonary capillary wedge pressure (PCWP) changes to identify the optimal time window for the noninvasive diagnostics of exercise-induced PCWP elevation. Methods and Results. Seventy-one patients at risk of heart failure with normal left ventricular ejection fraction underwent simultaneous exercise echocardiography and right heart catheterization. The ratio of early left ventricular filling velocity (E) to early diastolic mitral annular velocity (e') was used to predict noninvasively exercise-induced PCWP elevation. Fifty-one patients had exercise-induced PCWP elevation ≥ 8 mmHg and reached peak exercise PCWP ≥ 20 mmHg. Rapid post-exercise recovery of PCWP within 2 min was achieved in 18 (35.3%) patients. Intermediate postexercise PCWP recovery at 3 and 4 min was found in 16 (31.4%) patients while late post-exercise PCWP recovery (≥ 5 min) was achieved in 17 (33.3%) patients. Conclusion. The course of post-exercise PCWP recovery is highly variable, and a significant proportion of patients have only a brief period (≤ 2 min) of exercise-induced PCWP elevation. This fact should be taken into account in noninvasive assessment of exercise-induced PCWP.

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“…While there are a variety of confounders to this assessment (21)(22)(23), the E:E' parameter has broadly been adopted by the echocardiography community as in indicator of normal versus elevated LAP (20,24).…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

ePLAR - The echocardiographic pulmonary to left atrial ratio - a novel non-invasive parameter to differentiate pre-capillary and post-capillary pulmonary hypertension

Scalia¹,

Scalia

Kierle³

et al. 2015

Heart, Lung and Circulation

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., ePLAR -The echocardiographic pulmonary to left atrial ratio -A novel non-invasive parameter to differentiate pre-capillary and post-capillary pulmonary hypertension, International Journal of Cardiology (2016Cardiology ( ), doi: 10.1016Cardiology ( /j.ijcard.2016 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT AbstractBackground: Right heart catheterisation is the gold-standard for differentiating pre-capillary

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Do Additional Echocardiographic Variables Increase the Accuracy of E/e′ for Predicting Left Ventricular Filling Pressure in Normal Ejection Fraction? An Echocardiographic and Invasive Hemodynamic Study

Cited by 53 publications

References 38 publications

Obtaining accurate hemodynamics from echocardiography: achieving independence from right heart catheterization

Obtaining accurate hemodynamics from echocardiography: achieving independence from right heart catheterization

Variability of post-exercise pulmonary capillary wedge pressure recovery. Implications for noninvasive echocardiographic diagnostics

ePLAR - The echocardiographic pulmonary to left atrial ratio - a novel non-invasive parameter to differentiate pre-capillary and post-capillary pulmonary hypertension

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