DNA replication of bacteriophage θ29: Characterization of the intermediates and location of the termini of replication

Harding, Nancy E.; Ito, Junetsu

doi:10.1016/0042-6822(80)90337-2

Cited by 76 publications

(47 citation statements)

References 33 publications

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“…The apparent requirement for ATP is similar to that of the packaging reactions described for A (13,27), P22 (16), and P2 (17 (28), and the evidence suggests that the DNA replicates as a DNA-protein complex (6,29 …”

Section: Discussionmentioning

confidence: 55%

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In vitro assembly of the Bacillus subtilis bacteriophage phi 29.

Bjornsti¹,

Reilly²,

Anderson³

1981

Proc. Natl. Acad. Sci. U.S.A.

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Section: Discussionmentioning

confidence: 55%

“…Three genes appear to function exclusively in morphogenesis. The product of gene 3 initiates DNA replication, is covalently bound to the 5'-termini ofthe DNA (5,6), and has a role in DNA encapsidation (7).…”

mentioning

confidence: 99%

In vitro assembly of the Bacillus subtilis bacteriophage phi 29.

Bjornsti¹,

Reilly²,

Anderson³

1981

Proc. Natl. Acad. Sci. U.S.A.

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“…Replication of 029 is initiated at either DNA end (4)(5)(6) by the covalent attachment of 5'-dAMP to the serine residue 232 (7) of a free molecule of, the terminal protein p3 (8,9). The formation of the p3-dAMP initiation complex is catalyzed by the 029 DNA polymerase p2 (10,11) and requires the presence of a 029 DNA specific DNA template (12,13).…”

Section: Introductionmentioning

confidence: 99%

Replication of phage φ29 DNAin vitro: role of the viral protein p6 in initiation and elongation

et al. 1986

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“…It has been shown that X29 DNA-terminal protein is involved in its DNA replication and DNA encapsidation (8)(9)(10). HERMOSO and SALAS (I1) have shown that X29 terminal protein is linked to the DNA through a phosphoester bond To whom all correspondence should be addressed.…”

mentioning

confidence: 99%

Comparative studies on the small Bacillus bacteriophages.

Yoshikawa

Elder

Ito

1986

J. Gen. Appl. Microbiol.

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As an aid to a more rational classification of small Bacillus phages that contain DNA with terminal protein, we have compared genome size, physical maps, and electrophoretic patterns of the structural proteins of five bacteriophages (~29, 15, Nf, M2Y and GA-1). In addition, we compared tryptic and chymotryptic peptides of the major structural protein of these phages. The results allow the following conclusions. Five small phages can be classified into three groups: group A (~29 and 15), group B (Nf and M2Y) and group C (GA-1). The peptide maps of the major head protein of M2Y and Nf are very similar. On the other hand, the peptide maps of the GA-1 major head protein are not related to those of the other phages. Our present results suggest that although physical maps are quite different in group A and group B phages, the overall gene organization is similar in the two groups. On the other hand, group C phage, GA-l, is considerably different from the other two groups. These results argue that GA-1 phage have diverged very markedly from a common ancestor or were generated through a different evolutionary pathway.Bacillus phages X29, Xi5, M2, Nf and GA-1 are the smallest known bacteriophages which contain linear double-stranded DNA (1-3). The molecular weights of these viral genomes are about 11 to 13 x 106 daltons. The most interesting common features of these phages are that the genomes contain protein at their ends (4), and that the transfectivity of the DNA is sensitive to proteolytic enzymes (5-7).It has been shown that X29 DNA-terminal protein is involved in its DNA replication and DNA encapsidation (8-10). HERMOSO and SALAS (I1) have shown that X29 terminal protein is linked to the DNA through a phosphoester bond 1 2

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DNA replication of bacteriophage θ29: Characterization of the intermediates and location of the termini of replication

Cited by 76 publications

References 33 publications

In vitro assembly of the Bacillus subtilis bacteriophage phi 29.

In vitro assembly of the Bacillus subtilis bacteriophage phi 29.

Replication of phage φ29 DNAin vitro: role of the viral protein p6 in initiation and elongation

Comparative studies on the small Bacillus bacteriophages.

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