DNA Nanomachines: Aptamer‐Mediated Protein Molecular Recognition Driving a DNA Tweezer Nanomachine (Adv. Biosys. 1‐2/2017)

Abstract

In article number 1600006, Julian A. Tanner and co‐workers present a DNA nanotweezer, which is capable of detecting a target protein. A split aptamer is used for specific molecular recognition and response to malaria biomarker Plasmodium falciparum lactate dehydrogenase, thereby triggering G‐quadruplex hemin mediated peroxidase activity, which may be observed colorimetrically.