DNA-nanodiamond interactions influence on fluorescence of nanodiamonds

Abstract

In this study, the interaction between DNA and the surface of detonation nanodiamonds and nanodiamonds with NV centers is investigated, and the quantitative parameters of this interaction are calculated. The influence of interaction of DNA with nanodiamonds on the fluorescent properties of nanodiamonds is established. A correlation was found between the efficiency of DNA interaction with the surface of the detonation nanodiamonds and the changes of their fluorescence: the more DNA bonds with the nanodiamond surface groups -the stronger the fluorescence of detonation nanodiamonds increases in water.

The use of nanocluster polyoxometalates in the bioactive substance delivery systems

“…The biomedical aspect of nanodiamond use can also be considered [250][251][252][253][254][255][256][257][258][259][260]. The nanodispersed diamonds (or nanodiamonds) were obtained for the first time in in the USSR in the 1960s [261], but the widespread interest in the research of this material arose in the 1990s due to several factors.…”

“…The areas of nanodiamonds application are determined by their inherent outstanding qualities, both characteristic of diamonds in general and specific to nanodiamonds. Such properties as exceptional hardness, the Young's modulus, specific optical properties, biocompatibility, chemical stability, and fluorescence ability make nanodiamonds a promising material for biomedical applications [250][251][252][253][254][255][256][257][258][259][260][261][262][263]. Among the possible areas of biomedical application is the use as a matrix for tissue engineering, creation of implants and, in particular, bioactive substances targeted delivery [250,251,253,255,259].…”