2013
DOI: 10.1002/anie.201304038
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DNA Modification under Mild Conditions by Suzuki–Miyaura Cross‐Coupling for the Generation of Functional Probes

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Cited by 122 publications
(133 citation statements)
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“…In the field of homogenous Pd-mediated chemistry, Davis developed biomolecule compatible Pd-complexes and strategies to tag and modify peptides, sugars [19], proteins [20,21 ] and DNA [23]. Davis elegantly exemplified the in vitro labelling of biomolecules by incorporation of various chemical tags by chemical (e.g.…”
Section: Homogenous Pd-mediated Chemistrymentioning
confidence: 99%
“…In the field of homogenous Pd-mediated chemistry, Davis developed biomolecule compatible Pd-complexes and strategies to tag and modify peptides, sugars [19], proteins [20,21 ] and DNA [23]. Davis elegantly exemplified the in vitro labelling of biomolecules by incorporation of various chemical tags by chemical (e.g.…”
Section: Homogenous Pd-mediated Chemistrymentioning
confidence: 99%
“…This has been used to produce fluorescent phenyl-guanine or benzothiophene-guanine analogues 96 . A more reactive 5-iodothymine has also been explored that could undergo the coupling reaction at lower temperatures 97 . For Stille coupling, both 5-iodothymine and 2-iodoadenine have been explored to react with high excess of organostannane under the catalysis of palladium(0) triarylphosphine, heated to 60 °C in dimethylformamide 98,99 .…”
Section: Labelling Methodsmentioning
confidence: 99%
“…[35,42] [176] N-Arylierung ist eine leistungsfähige Methode zur Herstellung von N-C(sp 2 )-Bindungen in vielen Wirkstoffmolekülen und komplexen Naturstoffen. [182][183][184][185] Eine breite Auswahl von Arylhalogeniden und Arylboronsäuren ist im Handel erhältlich und steht als Bausteine fürd ie Modifikation von Aminen mittels der genannten Metall-katalysierten Reaktionen zur Verfügung. Eher routinemäßig angewendete Methoden fürd ie Arylierung von Aminen sind Übergangsmetall-katalysierte Kreuzkupplungen wie die Buchwald-Hartwig-Reaktion, [36,177,178] die Chan-Lam-Reaktion [179][180][181] sowie Ullmann-Goldberg-Kupplungen.…”
Section: Lysinarylierungunclassified