DNA methylation signatures in the prefrontal cortex of alcohol-naïve nonhuman primates predict risk for future ethanol drinking.
Rita Cervera Juanes,
Kip Zimmerman,
Larry Wilhelm
et al.
Abstract:Alcohol use disorder (AUD) is a highly prevalent, complex, multifactorial and heterogeneous disorder, with 11% and 30% of adults meeting criteria for past-year and lifetime AUD, respectively. Early and accurate identification of individuals at risk of developing an AUD would facilitate effective deployment of personalized interventions. Studies using rhesus monkeys1,2 and rats3, have demonstrated that individuals with low cognitive flexibility and a predisposition towards habitual behaviors show an increased r… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.