DNA Methylation of PXDN Is Associated with Early-Life Adversity in Adult Mental Disorders
Susanne Edelmann,
Jeysri Balaji,
Sarah Pasche
et al.
Abstract:Early-life adversity (ELA) is characterized by exposure to traumatic events during early periods of life, particularly involving emotional, sexual and/or physical adversities during childhood. Mental disorders are strongly influenced by environmental and lifestyle-related risk factors including ELA. However, the molecular link between ELA and the risk of an adult mental disorder is still not fully understood. Evidence is emerging that long-lasting changes in the epigenetic processes regulating gene expression,… Show more
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