DNA methylation in peripheral blood is associated with renal aging and renal function decline: a national community study
Po-Lung Yang,
Tai-Shuan Lai,
Yu-Hsiang Chou
et al.
Abstract:Background
Older patients are at risk for acute kidney injury and chronic kidney disease. Age-related increases in DNA methylation at CpG islands have been linked to aging-related diseases like cancer and cardiovascular disease, but the exact causal relationship between methylation in renal aging and other kidney diseases remains unclear. This study aimed to elucidate the methylation status of peripheral blood mononuclear cells (PBMCs) in the Asian population. Using human whole blood DNA methyl… Show more
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