Abstract:Mammalian genome has a profound effect of DNA methylation or covalent addition of a methyl group to cytosine with reference to CpG dinucleotide. These modifications are very stable but reversible. The effect of mutation of a number of Tumor suppressor gene (TSGs) can be mimicked by the change in methylation of promoter. Hypomethylation and
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.