DNA methylation clocks for estimating biological age in Chinese cohorts
Zikai Zheng,
Jiaming Li,
Tianzi Liu
et al.
Abstract:Epigenetic clocks are accurate predictors of human chronological age based on the analysis of DNA methylation at specific CpG sites. However, available DNA methylation (DNAm) age predictors are based on datasets with limited ethnic representation. Moreover, a systematic comparison between DNAm data and other omics datasets has not yet been performed. To address these knowledge gaps, we generated and analyzed DNA methylation datasets from two independent Chinese cohorts, revealing age-related DNAm changes. Addi… Show more
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