DNA‐Mediated Assembly of Gold Nanoparticles and Applications in Bioanalysis

Xue, Jianru; Chen, Feng; Bai, Min; Yu, Xu; Wei, Jing; Huang, Ping; Zhao, Yongxi

doi:10.1002/cnma.201700177

Cited by 18 publications

(7 citation statements)

References 111 publications

(224 reference statements)

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“…[25,26,[206][207][208] To prepare small NP dimers or trimers, multidentate ligands (e.g., dithiolates) are used to link together constituent particles. [74,209] To precisely assemble more complex 2D or 3D oligomers such as tetramers, pentamers, hexamers, heptamers, etc., the directional interactions between NPs introduced by polymer [143,210] or DNA ligands, [211][212][213] typically thiolated, [212] may be required. Designed ligands can be synthesized and introduced to the NP surface through ligand exchange, described in Section 2.…”

Section: Spherical-metal Np Artificial Metamoleculesmentioning

confidence: 99%

Chemical and Physical Properties of Photonic Noble‐Metal Nanomaterials

2022

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Colloidal noble metal nanoparticles (NPs) are composed of metal cores and organic or inorganic ligand shells. These NPs support size‐ and shape‐dependent plasmonic resonances. They can be assembled from dispersions into artificial metamolecules which have collective plasmonic resonances originating from coupled bright and dark optical electric and magnetic modes that form depending on the size and shape of the constituent NPs and their number, arrangement, and interparticle distance. NPs can also be assembled into extended 2D and 3D metamaterials that are glassy thin films or ordered thin films or crystals, also known as superlattices and supercrystals. The metamaterials have tunable optical properties that depend on the size, shape, and composition of the NPs, and on the number of NP layers and their interparticle distance. Interestingly, strong light‐matter interactions in superlattices form plasmon polaritons. Tunable interparticle distances allow designer materials with dielectric functions tailorable from that characteristic of an insulator to that of a metal, and serve as strong optical absorbers or scatterers, respectively. In combination with lithography techniques, these extended assemblies can be patterned to create subwavelength NP superstructures and form large‐area 2D and 3D metamaterials that manipulate the amplitude, phase, and polarization of transmitted or reflected light.

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Section: Spherical-metal Np Artificial Metamoleculesmentioning

confidence: 99%

Chemical and Physical Properties of Photonic Noble‐Metal Nanomaterials

2022

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“… 14 , 15 , 16 , 17 Among them, AuNPs have become one of the most widely used nanomaterials in the construction of DNA nanomachines. 18 AuNPs, usually in the size of 1–100 nm, could display unique optical properties by adjusting their size and shape, rendering them a typical nanomaterial for surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) analysis. 19 , 20 The aggregation state of AuNPs can indicate the color change of the solution.…”

Section: Introductionmentioning

confidence: 99%

Advances in self-assembled Au-DNA nanomachines

Zhang¹,

Xu²,

Zheng³

et al. 2023

iScience

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“…These unique properties enable nanomaterials to be used as sensing probes, contrast agents, therapeutic agents, and drug delivery systems that provide a new modality to solve the current clinical tumor treatment problems. [2][3][4][5][6] Nanomaterials are widely used in fundamental research concerning cancer diagnosis and therapy to make nanotechnology feasible for clinical application. It is highly meaningful to integrate different imaging and treatment methods into one system and construct a multifunctional nanostructure system for imaging, drug delivery, and therapy.…”

Section: Introductionmentioning

confidence: 99%

Plasmonic gold nanoagents for cancer imaging and therapy

Zhang

Song

et al. 2021

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Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high electron density and atomic number, superparamagnetic properties, and radiation sensitization effect, and their optical absorbance can be adjusted to the required biological window; thus, AuNPs are suitable for cancer imaging (photoacoustic imaging, computed tomography, and magnetic resonance imaging), photothermal therapy, and radiotherapy. AuNPs can also be used as carriers to load photosensitizers or chemotherapeutic agents, and therefore, can also be used in photodynamic therapy and chemotherapy. In summary, AuNPs and their assemblies can simultaneously realize cancer diagnosis and treatment, providing a new idea in the development of precision medical treatment.

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DNA‐Mediated Assembly of Gold Nanoparticles and Applications in Bioanalysis

Cited by 18 publications

References 111 publications

Chemical and Physical Properties of Photonic Noble‐Metal Nanomaterials

Chemical and Physical Properties of Photonic Noble‐Metal Nanomaterials

Advances in self-assembled Au-DNA nanomachines

Plasmonic gold nanoagents for cancer imaging and therapy

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